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NCT01897792 · ClinicalTrials.gov registry record · Phase 2
Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma
A Phase 2 study, sponsored by University of Alabama at Birmingham.
- Terminated
- Registry status
- Phase 2
- Development phase
- 11
- Enrollment target
NCT01897792: Clinical Trial Phase 2 study, sponsored by University of Alabama at Birmingham.
NCT01897792 is a Phase 2 study that was terminated before completion, run by University of Alabama at Birmingham. The registered enrollment target is 11 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01897792, a Phase 2 study, was terminated before completion, sponsored by University of Alabama at Birmingham.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 11 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the effect of antioxidant vitamins (vitamins C and E) on the development of coagulation derangements and nosocomial pneumonia after severe trauma in patients.
Primary Outcome
Coagulation parameters are evaluated using standard functional tests (prothrombin time (PT), partial thromboplastin time (PTT), fibrinogen and platelet count)and point of care functional analysis using thromboelastogram (TEG-ROTEM). A blood sample is collected upon arrival in the emergency department at 0 hours only and analyzed for markers of activation of coagulation, inflammation, and levels of vitamin C/E.
Interventions
- DIETARY_SUPPLEMENT Vitamin C
- DIETARY_SUPPLEMENT Vitamin E
- DIETARY_SUPPLEMENT Saline (for Vitamin C)
- DRUG Placebo (for Vitamin E)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2013-05 |
| Est. Completion | 2015-02 |
| Phase | Phase 2 |
Why NCT01897792 stopped before completion
NCT01897792 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 4 interventions - of which Vitamin C is the first listed.
NCT01897792 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01897792 about?
NCT01897792 is a clinical study titled "Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma". The purpose of this study is to determine the effect of antioxidant vitamins (vitamins C and E) on the development of coagulation derangements and nosocomial pneumonia after severe trauma in patients.
What is the current status of trial NCT01897792?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 11 participants. The study started on 2013-05. Estimated completion is 2015-02.
What interventions are being tested in trial NCT01897792?
The interventions under investigation include: Vitamin C (DIETARY_SUPPLEMENT), Vitamin E (DIETARY_SUPPLEMENT), Saline (for Vitamin C) (DIETARY_SUPPLEMENT), Placebo (for Vitamin E) (DRUG).
Who is sponsoring clinical trial NCT01897792?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01897792's enrollment target sits among peer trials
11 1967th of 2000 higher than 33 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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