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NCT01892293 · ClinicalTrials.gov registry record · Phase 1

CT Antigen TCR-Engineered T Cells for Myeloma

A Phase 1 study, sponsored by Adaptimmune.

Terminated
Registry status
Phase 1
Development phase
6
Enrollment target

NCT01892293: Clinical Trial Phase 1 study, sponsored by Adaptimmune.

NCT01892293 is a Phase 1 study that was terminated before completion, run by Adaptimmune. The registered enrollment target is 6 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01892293, a Phase 1 study, was terminated before completion, sponsored by Adaptimmune.

TERMINATED
Registry status
Phase 1
Development phase
6 participants
Enrollment target

Study Summary

This study will enroll patients with multiple myeloma who have received prior therapy for their disease but their disease has progressed or relapsed.

Primary Outcome

Number of Participants with NCI CTCAE Version 4.0 Adverse Events related to study treatment greater than or equal to Grade 3

Interventions

  • DRUG Treatment with NY-ESO-1c259-modified T cells

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2013-10-15
Est. Completion 2018-04-09
Phase Phase 1
Adaptimmune

13 total trials

Why NCT01892293 stopped before completion

NCT01892293 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 1 intervention - of which Treatment with NY-ESO-1c259-modified T cells is the first listed.

NCT01892293 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01892293 about?

NCT01892293 is a clinical study titled "CT Antigen TCR-Engineered T Cells for Myeloma". This study will enroll patients with multiple myeloma who have received prior therapy for their disease but their disease has progressed or relapsed.

What is the current status of trial NCT01892293?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2013-10-15. Estimated completion is 2018-04-09.

What interventions are being tested in trial NCT01892293?

The interventions under investigation include: Treatment with NY-ESO-1c259-modified T cells (DRUG).

Who is sponsoring clinical trial NCT01892293?

This trial is sponsored by Adaptimmune, which has 13 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01892293's enrollment target sits among peer trials

6 1974th of 2000 higher than 12 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01892293, the US trial registry maintained by the National Library of Medicine. NCT01892293 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.