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NCT01890967 · ClinicalTrials.gov registry record · Phase 2

A Study of LY3015014 in Participants With High Cholesterol

A Phase 2 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 2
Development phase
527
Enrollment target

NCT01890967: Completed Phase 2 study, sponsored by Eli Lilly and Company.

NCT01890967 is a Phase 2 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 527 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (296% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01890967, a Phase 2 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 2
Development phase
527 participants
Enrollment target

Study Summary

This study is designed to define the amount and duration of cholesterol lowering and to assess the safety and tolerability of different dose regimens of LY3015014 in participants with high cholesterol. The study will also investigate how the body processes the drug and how the drug affects the body. Participants will remain on a stable diet and will continue taking cholesterol-lowering medications (statins with or without ezetimibe). After signing the informed consent document, the participant will complete a screening/run-in period that will last at most 8 weeks. Then, the treatment period will last approximately 16 weeks. After the treatment period, the participants will complete a follow-up period lasting approximately 8 weeks for a total study duration ranging from approximately 25 to 32 weeks.

Primary Outcome

Least square (LS) Means was calculated using analysis of covariance (ANCOVA) adjusted for disease classification, statin dose, baseline LDL-C measurement. Percent change from baseline response is the dependent variable.

Interventions

  • DRUG Placebo
  • DRUG Ezetimibe
  • DRUG Statin
  • DRUG LY3015014

Trial Details

FieldValue
Enrollment Target 527 participants
Start Date 2013-06
Est. Completion 2014-06
Phase Phase 2
Eli Lilly and Company

1,341 total trials

What the finished NCT01890967 record still lists

NCT01890967 is an interventional study that assigns participants to a tested intervention. The registered 527 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (296% higher).

The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.

NCT01890967 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01890967 about?

NCT01890967 is a clinical study titled "A Study of LY3015014 in Participants With High Cholesterol". This study is designed to define the amount and duration of cholesterol lowering and to assess the safety and tolerability of different dose regimens of LY3015014 in participants with high cholesterol. The study will also investigate how the body processes the drug and how the drug affects the body....

What is the current status of trial NCT01890967?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 527 participants. The study started on 2013-06. Estimated completion is 2014-06.

What interventions are being tested in trial NCT01890967?

The interventions under investigation include: Placebo (DRUG), Ezetimibe (DRUG), Statin (DRUG), LY3015014 (DRUG).

Who is sponsoring clinical trial NCT01890967?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01890967's enrollment target sits among peer trials

527 65th of 2000 higher than 1,936 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01890967, the US trial registry maintained by the National Library of Medicine. NCT01890967 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.