Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01876758 · ClinicalTrials.gov registry record · NA

Cognitive Training for Memory Deficits Associated With Electroconvulsive Therapy

A NA study, sponsored by New York State Psychiatric Institute.

Completed
Registry status
NA
Development phase
59
Enrollment target

NCT01876758: Completed NA study, sponsored by New York State Psychiatric Institute.

NCT01876758 is a NA study that has completed, run by New York State Psychiatric Institute. The registered enrollment target is 59 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01876758, a NA study, has completed, sponsored by New York State Psychiatric Institute.

COMPLETED
Registry status
NA
Development phase
59 participants
Enrollment target

Study Summary

Although electroconvulsive therapy (ECT) remains the most effective treatment for people with severe depression, patients may experience a significant degree of persistent and/or permanent memory problems following ECT. Many patients report the memory problems are the most disturbing and serious side effect of ECT, and that such effects impact their quality of life following treatment and their willingness to consent to further ECT needed to complete a treatment course or to maintain remission. New developments in the field of cognitive remediation have demonstrated the benefits of cognitive training to improve memory performance in various conditions, such as epilepsy. However, these strategies have never been applied to help patients regain memory after ECT. The investigators have designed and piloted a novel cognitive program specifically targeted to the cognitive effects of ECT, based upon a program tailored to people with seizure disorders, a group with memory problems very similar to people who undergo ECT. This Memory Training for ECT (Mem-ECT) is designed to help cognitive functions that may be compromised following ECT remain relatively preserved. In addition, the intervention attempts to help ECT patients quickly regain their general memory skills immediately following ECT. Recent results from our preliminary group of patients who underwent ECT and memory training at New York Presbyterian shows no overall decline in memory function following ECT. On the basis of these promising findings, the investigators propose a more rigorous and larger study to confirm whether this novel memory training program can help alleviate memory problems associated with ECT.

Interventions

  • BEHAVIORAL Cognitive Intervention: Memory Training
  • BEHAVIORAL Comparable general mental stimulation

Trial Details

FieldValue
Enrollment Target 59 participants
Start Date 2012-09
Est. Completion 2017-05
Phase NA

What the finished NCT01876758 record still lists

NCT01876758 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 59 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 2 interventions - of which Cognitive Intervention: Memory Training is the first listed.

NCT01876758 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01876758 about?

NCT01876758 is a clinical study titled "Cognitive Training for Memory Deficits Associated With Electroconvulsive Therapy". Although electroconvulsive therapy (ECT) remains the most effective treatment for people with severe depression, patients may experience a significant degree of persistent and/or permanent memory problems following ECT. Many patients report the memory problems are the most disturbing and serious sid...

What is the current status of trial NCT01876758?

This trial is currently completed. It is a NA study. The enrollment target is 59 participants. The study started on 2012-09. Estimated completion is 2017-05.

What interventions are being tested in trial NCT01876758?

The interventions under investigation include: Cognitive Intervention: Memory Training (BEHAVIORAL), Comparable general mental stimulation (BEHAVIORAL).

Who is sponsoring clinical trial NCT01876758?

This trial is sponsored by New York State Psychiatric Institute, which has 364 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01876758's enrollment target sits among peer trials

59 1256th of 2000 higher than 745 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03801083 · 59 participants · Phase 2

    Adoptive Transfer of Tumor Infiltrating Lymphocytes for Biliary Tract Cancers

  • NCT04332367 · 59 participants · Phase 2

    Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance

  • NCT05489575 · 59 participants · NA

    CPAP for the Treatment of Supine Hypertension

  • NCT06721689 · 59 participants · Phase 1

    PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01876758, the US trial registry maintained by the National Library of Medicine. NCT01876758 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.