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NCT01871402 · ClinicalTrials.gov registry record · Phase 3
A Comparison of 000-0551 Lotion Versus Vehicle Lotion in Subjects With Plaque Psoriasis (Study -304)
A Phase 3 study of Plaque Psoriasis, sponsored by Therapeutics.
- Completed
- Registry status
- Phase 3
- Development phase
- 221
- Enrollment target
- 10
- Study locations
NCT01871402: Completed Phase 3 study of Plaque Psoriasis, sponsored by Therapeutics.
NCT01871402 is a Phase 3 study of Plaque Psoriasis that has completed, run by Therapeutics. The registered enrollment target is 221 participants, below the 411-participant average among 45 other Plaque Psoriasis trials with a reported enrollment target (46% lower). The trial reports 10 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01871402, a Phase 3 study of Plaque Psoriasis, has completed, sponsored by Therapeutics.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 221 participants
- Enrollment target
- 10
- Study locations
Study Summary
This Phase 3 study has been designed to determine and compare the efficacy and safety of 000-0551 Lotion and Vehicle Lotion applied twice daily for two weeks in subjects with plaque psoriasis.
Primary Outcome
The IGA score is a static evaluation of the overall or "average" degree of severity of a subject's disease, taking into account all of the subject's psoriatic lesions. "Treatment success" is defined as a score of 0 or 1 representing "cleared" or "almost cleared" at Day 15 with at least a two grade decrease in severity score relative to Baseline. IGA is measured on a 5-point scale, ranging from 0 (clear) to 4 (severe/very severe).
Conditions Studied
Interventions
- DRUG 000-0551 Lotion
- DRUG Vehicle Lotion
Study Locations (10)
California
- Center for Dermatology Clinical Research, Inc. - Fremont
- UCSD Dermatology - San Diego
Illinois
- Altman Dermatology Associates - Arlington Heights
Michigan
- Henry Ford Health System - Detroit
Minnesota
- Minnesota Clinical Study Center - Fridley
North Carolina
- Wilmington Dermatology Center - Wilmington
Oregon
- Oregon Medical Research Center, PC - Portland
Rhode Island
- Clinical Partners, LLC - Johnston
Texas
- Research Across America - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 221 participants |
| Start Date | 2013-05 |
| Est. Completion | 2013-12 |
| Phase | Phase 3 |
What the finished NCT01871402 record still lists
NCT01871402 is an interventional study that assigns participants to a tested intervention. The registered 221 participants enrollment target is mid-sized for trials with a published cap, below the 411-participant average among 45 other Plaque Psoriasis trials with a reported enrollment target (46% lower).
The record links to 1 condition, with Plaque Psoriasis appearing as the primary indexed condition, and to 2 interventions - of which 000-0551 Lotion is the first listed.
NCT01871402 lists 10 locations in 9 states (California, Illinois, Michigan).
Frequently Asked Questions
What is clinical trial NCT01871402 about?
NCT01871402 is a clinical study titled "A Comparison of 000-0551 Lotion Versus Vehicle Lotion in Subjects With Plaque Psoriasis (Study -304)". This Phase 3 study has been designed to determine and compare the efficacy and safety of 000-0551 Lotion and Vehicle Lotion applied twice daily for two weeks in subjects with plaque psoriasis.
What is the current status of trial NCT01871402?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 221 participants. The study started on 2013-05. Estimated completion is 2013-12.
What conditions does trial NCT01871402 study?
This clinical trial studies the following conditions: Plaque Psoriasis.
What interventions are being tested in trial NCT01871402?
The interventions under investigation include: 000-0551 Lotion (DRUG), Vehicle Lotion (DRUG).
Who is sponsoring clinical trial NCT01871402?
This trial is sponsored by Therapeutics, which has 17 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01871402 being conducted?
This trial has 10 study locations across California, Illinois, Michigan, Minnesota, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Plaque Psoriasis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01871402's enrollment target sits among peer trials
221 20th of 45 higher than 26 of 45 other Plaque Psoriasis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Plaque Psoriasis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
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-
A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis
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A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis
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