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NCT01870375 · ClinicalTrials.gov registry record
Longitudinal Studies of Brain Structure and Function in MPS Disorders
A clinical trial of Mucopolysaccharidosis Type I and Mucopolysaccharidosis Type II, sponsored by University of Minnesota.
- Completed
- Registry status
- 100
- Enrollment target
- 4
- Study locations
NCT01870375: Completed study of Mucopolysaccharidosis Type I and Mucopolysaccharidosis Type II, sponsored by University of Minnesota.
NCT01870375 is a study of Mucopolysaccharidosis Type I and Mucopolysaccharidosis Type II that has completed, run by University of Minnesota. The registered enrollment target is 100 participants. The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01870375, a study of Mucopolysaccharidosis Type I and Mucopolysaccharidosis Type II, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- 100 participants
- Enrollment target
- 4
- Study locations
Study Summary
Neurobehavioral function and quality of life are compromised in many patients with mucopolysaccharidosis (MPS) disorders. The long-term goals of this research are to: 1) more accurately inform patients/parents regarding potential neurobehavioral outcomes; 2) develop sensitive measures of disease progression and central nervous system (CNS) treatment outcome; and 3) help clinical researchers develop direct treatments for specific brain structures/functions. The investigators hypothesize that specific and localized neuroimaging and neuropsychological findings and their relationship will be distinct for each MPS disorder. It is further hypothesized that without treatment, functions will decline and structure will change over time in a predictable fashion, and will be related to locus of abnormality and stage of disease.
Primary Outcome
Age-appropriate IQ tests will be administered at baseline and during subject's annual visit.
Conditions Studied
Study Locations (4)
California
- Oakland Children's Hospital - Oakland
Minnesota
- University of Minnesota - Minneapolis
New York
- New York University - New York
Ontario
- Hospital for Sick Children - Toronto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2009-09 |
| Est. Completion | 2019-08-31 |
What the finished NCT01870375 record still lists
NCT01870375 is an observational study that tracks outcomes without assigning an intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap.
The record links to 5 conditions, with Mucopolysaccharidosis Type I appearing as the primary indexed condition, and to 0 interventions.
NCT01870375 reports a single indexed study location in California, Minnesota, New York.
Frequently Asked Questions
What is clinical trial NCT01870375 about?
NCT01870375 is a clinical study titled "Longitudinal Studies of Brain Structure and Function in MPS Disorders". Neurobehavioral function and quality of life are compromised in many patients with mucopolysaccharidosis (MPS) disorders. The long-term goals of this research are to: 1) more accurately inform patients/parents regarding potential neurobehavioral outcomes; 2) develop sensitive measures of disease pro...
What is the current status of trial NCT01870375?
This trial is currently completed. The enrollment target is 100 participants. The study started on 2009-09. Estimated completion is 2019-08-31.
What conditions does trial NCT01870375 study?
This clinical trial studies the following conditions: Mucopolysaccharidosis Type I, Mucopolysaccharidosis Type II, Mucopolysaccharidosis Type VI, Mucopolysaccharidosis Type IV, Mucopolysaccharidosis Type VII.
Who is sponsoring clinical trial NCT01870375?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01870375 being conducted?
This trial has 4 study locations across California, Minnesota, New York, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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