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NCT05634512 · ClinicalTrials.gov registry record

Evaluation of Intravenous Laronidase Pharmacokinetics Before and After Hematopoietic Cell Transplantation in Patients With Mucopolysaccharidosis Type IH.

A clinical trial of Hematopoietic Cell Transplantation and Mucopolysaccharidosis Type I, sponsored by Masonic Cancer Center, University of Minnesota.

Active
Registry status
13
Enrollment target
1
Study location

NCT05634512 is a study of Hematopoietic Cell Transplantation and Mucopolysaccharidosis Type I that is active but no longer recruiting, run by Masonic Cancer Center, University of Minnesota. The registered enrollment target is 13 participants, below the 236-participant average among 4 other Hematopoietic Cell Transplantation trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05634512, a study of Hematopoietic Cell Transplantation and Mucopolysaccharidosis Type I, is active but no longer recruiting, sponsored by Masonic Cancer Center, University of Minnesota.

ACTIVE NOT RECRUITING
Registry status
13 participants
Enrollment target
1
Study location

Study Summary

This is a prospective, observational multicenter study to collect blood from patients with mucopolysaccharidosis type IH undergoing laronidase therapy and a stem cell transplant. Sixteen patients will be enrolled over a 24 month period.

Interventions

  • DRUG Laronidase therapy and a stem cell transplant

Study Locations (1)

Minnesota

  • University of Minnesota Masonic Cancer Center - Minneapolis

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2022-11-17
Est. Completion 2026-10-01

What the Registry Record Tells You About NCT05634512

The ClinicalTrials.gov registry entry for NCT05634512 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 13 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 236-participant average among 4 other Hematopoietic Cell Transplantation trials with a reported enrollment target (94% lower). The listed sponsor is Masonic Cancer Center, University of Minnesota, which has 249 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Hematopoietic Cell Transplantation appearing as the primary indexed condition, and to 1 intervention - of which Laronidase therapy and a stem cell transplant is the first listed.

NCT05634512 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT05634512 about?

NCT05634512 is a clinical study titled "Evaluation of Intravenous Laronidase Pharmacokinetics Before and After Hematopoietic Cell Transplantation in Patients With Mucopolysaccharidosis Type IH.". This is a prospective, observational multicenter study to collect blood from patients with mucopolysaccharidosis type IH undergoing laronidase therapy and a stem cell transplant. Sixteen patients will be enrolled over a 24 month period.

What is the current status of trial NCT05634512?

This trial is currently active not recruiting. The enrollment target is 13 participants. The study started on 2022-11-17. Estimated completion is 2026-10-01.

What conditions does trial NCT05634512 study?

This clinical trial studies the following conditions: Hematopoietic Cell Transplantation, Mucopolysaccharidosis Type I.

What interventions are being tested in trial NCT05634512?

The interventions under investigation include: Laronidase therapy and a stem cell transplant (DRUG).

Who is sponsoring clinical trial NCT05634512?

This trial is sponsored by Masonic Cancer Center, University of Minnesota, which has 249 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05634512 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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