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NCT01869114 · ClinicalTrials.gov registry record · Phase 2

Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy

A Phase 2 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University.

Completed
Registry status
Phase 2
Development phase
57
Enrollment target

NCT01869114 is a Phase 2 study that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University. The registered enrollment target is 57 participants.

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The verdict

NCT01869114, a Phase 2 study, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University.

COMPLETED
Registry status
Phase 2
Development phase
57 participants
Enrollment target

Study Summary

This phase II trial studies how well sirolimus and azacitidine works in treating patients with high-risk myelodysplastic syndrome or recurrent acute myeloid leukemia. Sirolimus may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Sirolimus and azacitidine may kill more cancer cells.

Interventions

  • DRUG Sirolimus
  • DRUG Azacitidine

Trial Details

FieldValue
Enrollment Target 57 participants
Start Date 2013-07-08
Est. Completion 2024-01-03
Phase Phase 2

What the Registry Record Tells You About NCT01869114

The ClinicalTrials.gov registry entry for NCT01869114 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 57 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University, which has 138 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Sirolimus is the first listed.

NCT01869114 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01869114 about?

NCT01869114 is a clinical study titled "Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy". This phase II trial studies how well sirolimus and azacitidine works in treating patients with high-risk myelodysplastic syndrome or recurrent acute myeloid leukemia. Sirolimus may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, suc...

What is the current status of trial NCT01869114?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 57 participants. The study started on 2013-07-08. Estimated completion is 2024-01-03.

What interventions are being tested in trial NCT01869114?

The interventions under investigation include: Sirolimus (DRUG), Azacitidine (DRUG).

Who is sponsoring clinical trial NCT01869114?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University, which has 138 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.