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NCT01854268 · ClinicalTrials.gov registry record · Phase 1
Respiratory Kinematics During Voluntary and Reflex Cough in Healthy Adults
A Phase 1 study, sponsored by University of Florida.
- Completed
- Registry status
- Phase 1
- Development phase
- 25
- Enrollment target
NCT01854268: Completed Phase 1 study, sponsored by University of Florida.
NCT01854268 is a Phase 1 study that has completed, run by University of Florida. The registered enrollment target is 25 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01854268, a Phase 1 study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 25 participants
- Enrollment target
Study Summary
Cough is a defensive behavior that involves three stages. A large inspiratory phase, a compression phase where the vocal folds close and subglottal pressure is developed, and an expiratory phase. Cough serves to protect the upper and lower airways from material such as liquids, solids, or saliva, that have been aspirated. There are two types of cough: voluntary and reflex cough. Voluntary cough involves a cough to command. Reflex cough is a cough that is generated secondary to a stimulus in or near the airway. There has been some research regarding the differences between voluntary and reflex cough. However, no research has described the differences in airflow or movement pattern (kinematics) between the two types of cough. This study seeks to determine the respiratory kinematics and airflow differences between voluntary and reflex cough in healthy participants.
Primary Outcome
Respiratory kinematic measure: lung volume initiation (LVI) Lung volume initiation is a measure of the volume of air in the lungs prior to a respiratory task.
Interventions
- DRUG Healthy adults who receive capsaicin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2013-05 |
| Est. Completion | 2014-05 |
| Phase | Phase 1 |
What the finished NCT01854268 record still lists
NCT01854268 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower).
The record links to 0 conditions, and to 1 intervention - of which Healthy adults who receive capsaicin is the first listed.
NCT01854268 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01854268 about?
NCT01854268 is a clinical study titled "Respiratory Kinematics During Voluntary and Reflex Cough in Healthy Adults". Cough is a defensive behavior that involves three stages. A large inspiratory phase, a compression phase where the vocal folds close and subglottal pressure is developed, and an expiratory phase. Cough serves to protect the upper and lower airways from material such as liquids, solids, or saliva, th...
What is the current status of trial NCT01854268?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2013-05. Estimated completion is 2014-05.
What interventions are being tested in trial NCT01854268?
The interventions under investigation include: Healthy adults who receive capsaicin (DRUG).
Who is sponsoring clinical trial NCT01854268?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01854268's enrollment target sits among peer trials
25 1495th of 2000 higher than 481 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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