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NCT01853696 · ClinicalTrials.gov registry record · Phase 4
Comparison of Corticosteroid Dosing Regimens After Endothelial Keratoplasty
A Phase 4 study, sponsored by Cornea Research Foundation of America.
- Completed
- Registry status
- Phase 4
- Development phase
- 167
- Enrollment target
NCT01853696: Completed Phase 4 study, sponsored by Cornea Research Foundation of America.
NCT01853696 is a Phase 4 study that has completed, run by Cornea Research Foundation of America. The registered enrollment target is 167 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01853696, a Phase 4 study, has completed, sponsored by Cornea Research Foundation of America.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 167 participants
- Enrollment target
Study Summary
Graft rejection has traditionally been one of the leading causes of cornea transplant failure. To help prevent rejection, corticosteroid eye drops are used for an extended period after transplant surgery. The purpose of this study is to compare the efficacy and side effects of different corticosteroid dosing regimens after endothelial keratoplasty (cornea transplant) surgery.
Primary Outcome
Number of eyes in which the absolute intraocular pressure equaled or exceeded 24 mm Hg OR in which there was a relative increase of at least 10 mm Hg over the baseline preoperative reading.
Interventions
- DRUG loteprednol etabonate
- DRUG prednisolone acetate 1%
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 167 participants |
| Start Date | 2013-03 |
| Est. Completion | 2015-01 |
| Phase | Phase 4 |
What the finished NCT01853696 record still lists
NCT01853696 is an interventional study that assigns participants to a tested intervention. The registered 167 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (68% lower).
The record links to 0 conditions, and to 2 interventions - of which loteprednol etabonate is the first listed.
NCT01853696 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01853696 about?
NCT01853696 is a clinical study titled "Comparison of Corticosteroid Dosing Regimens After Endothelial Keratoplasty". Graft rejection has traditionally been one of the leading causes of cornea transplant failure. To help prevent rejection, corticosteroid eye drops are used for an extended period after transplant surgery. The purpose of this study is to compare the efficacy and side effects of different corticostero...
What is the current status of trial NCT01853696?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 167 participants. The study started on 2013-03. Estimated completion is 2015-01.
What interventions are being tested in trial NCT01853696?
The interventions under investigation include: loteprednol etabonate (DRUG), prednisolone acetate 1% (DRUG).
Who is sponsoring clinical trial NCT01853696?
This trial is sponsored by Cornea Research Foundation of America, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01853696's enrollment target sits among peer trials
167 488th of 2000 higher than 1,512 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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