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NCT01843790 · ClinicalTrials.gov registry record · Phase 2

A Phase 2a Study of Weekly Doses of GCS-100 in Patients With Chronic Kidney Disease

A Phase 2 study, sponsored by La Jolla Pharmaceutical Company.

Completed
Registry status
Phase 2
Development phase
120
Enrollment target

NCT01843790: Completed Phase 2 study, sponsored by La Jolla Pharmaceutical Company.

NCT01843790 is a Phase 2 study that has completed, run by La Jolla Pharmaceutical Company. The registered enrollment target is 120 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (10% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT01843790, a Phase 2 study, has completed, sponsored by La Jolla Pharmaceutical Company.

COMPLETED
Registry status
Phase 2
Development phase
120 participants
Enrollment target

Study Summary

The primary objective of this study is to compare the change in estimated glomerular filtration rate (eGFR) from baseline to Week 8 between placebo and GCS-100 treatment. The secondary objective is to determine the safety and tolerability of GCS-100 administered for 8 weeks relative to placebo. In addition, the study will measure the effect of GCS-100 on circulating galectin-3 and other markers of disease activity.

Interventions

  • DRUG GCS-100
  • DRUG Placebo, Saline

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2013-06
Est. Completion 2014-09
Phase Phase 2
La Jolla Pharmaceutical Company

12 total trials

What the finished NCT01843790 record still lists

NCT01843790 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (10% lower).

The record links to 0 conditions, and to 2 interventions - of which GCS-100 is the first listed.

NCT01843790 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01843790 about?

NCT01843790 is a clinical study titled "A Phase 2a Study of Weekly Doses of GCS-100 in Patients With Chronic Kidney Disease". The primary objective of this study is to compare the change in estimated glomerular filtration rate (eGFR) from baseline to Week 8 between placebo and GCS-100 treatment. The secondary objective is to determine the safety and tolerability of GCS-100 administered for 8 weeks relative to placebo. In a...

What is the current status of trial NCT01843790?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 120 participants. The study started on 2013-06. Estimated completion is 2014-09.

What interventions are being tested in trial NCT01843790?

The interventions under investigation include: GCS-100 (DRUG), Placebo, Saline (DRUG).

Who is sponsoring clinical trial NCT01843790?

This trial is sponsored by La Jolla Pharmaceutical Company, which has 12 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01843790's enrollment target sits among peer trials

120 569th of 2000 higher than 1,383 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01843790, the US trial registry maintained by the National Library of Medicine. NCT01843790 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.