Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01842529 · ClinicalTrials.gov registry record · Phase 2
Botulinum Toxin Injection in Epicardial Fat Pads To Treat Atrial Fibrillation After Cardiac Surgery
A Phase 2 study, sponsored by Meshalkin Research Institute of Pathology of Circulation.
- Completed
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
NCT01842529: Completed Phase 2 study, sponsored by Meshalkin Research Institute of Pathology of Circulation.
NCT01842529 is a Phase 2 study that has completed, run by Meshalkin Research Institute of Pathology of Circulation. The registered enrollment target is 60 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01842529, a Phase 2 study, has completed, sponsored by Meshalkin Research Institute of Pathology of Circulation.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
Study Summary
The aim of this prospective randomized double-blind study was to compare the efficacy and safety of Botulinum toxin injection in epicardial fat pads for preventing recurrences (in early postoperative period) of atrial tachyarrhythmia in patients with paroxysmal atrial fibrillation undergoing coronary artery bypass graft (CABG) surgery.
Interventions
- BIOLOGICAL botulinum toxin injection
- BIOLOGICAL 0.9% normal saline injection
- DEVICE Implantable loop recorder
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2012-09 |
| Est. Completion | 2013-12 |
| Phase | Phase 2 |
What the finished NCT01842529 record still lists
NCT01842529 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower).
The record links to 0 conditions, and to 3 interventions - of which botulinum toxin injection is the first listed.
NCT01842529 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01842529 about?
NCT01842529 is a clinical study titled "Botulinum Toxin Injection in Epicardial Fat Pads To Treat Atrial Fibrillation After Cardiac Surgery". The aim of this prospective randomized double-blind study was to compare the efficacy and safety of Botulinum toxin injection in epicardial fat pads for preventing recurrences (in early postoperative period) of atrial tachyarrhythmia in patients with paroxysmal atrial fibrillation undergoing coronar...
What is the current status of trial NCT01842529?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2012-09. Estimated completion is 2013-12.
What interventions are being tested in trial NCT01842529?
The interventions under investigation include: botulinum toxin injection (BIOLOGICAL), 0.9% normal saline injection (BIOLOGICAL), Implantable loop recorder (DEVICE).
Who is sponsoring clinical trial NCT01842529?
This trial is sponsored by Meshalkin Research Institute of Pathology of Circulation, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01842529's enrollment target sits among peer trials
60 1027th of 2000 higher than 868 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00576069 · 60 participants
Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma
- NCT01297400 · 60 participants · Phase 2
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
- NCT01734122 · 60 participants
Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor
- NCT01804634 · 60 participants · Phase 2
Reduced Intensity Haploidentical BMT for High Risk Solid Tumors
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia