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NCT01841840 · ClinicalTrials.gov registry record · NA
The Acute Effects of Passive Vibration on Cardiovascular Function in Individuals With Stroke
A NA study, sponsored by Florida State University.
- Completed
- Registry status
- NA
- Development phase
- 11
- Enrollment target
NCT01841840: Completed NA study, sponsored by Florida State University.
NCT01841840 is a NA study that has completed, run by Florida State University. The registered enrollment target is 11 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01841840, a NA study, has completed, sponsored by Florida State University.
- COMPLETED
- Registry status
- NA
- Development phase
- 11 participants
- Enrollment target
Study Summary
Stroke is the third leading cause of death in the United States. Of those who are affected by stroke, a third becomes permanently disabled. Risk factors for stroke include, but are not limited to, advancing age, physical inactivity, arterial stiffness, and most commonly, high blood pressure. Stroke is a major form of a much boarder problem, cardiovascular disease (CVD). CVD is considered the primary cause of death in the US. Interestingly, increased arterial stiffness of elastic arteries (carotid and aorta) has been shown to be strongly correlated to CVD and stroke. Increased arterial stiffness is considered an independent risk for the development of CVD and stroke. Hence, arterial stiffness has been suggested as a potential therapeutic target for CVD and more specifically stroke. Recently, whole-body vibration (WBV) exercise has been proposed as a new and effective method to improve muscle mass and muscle strength in younger and older individuals. It is known that systemic arterial stiffness decreased 40 min after a single WBV session in healthy men. In our laboratory, we have shown that leg arterial stiffness decreases after a session of WBV. Taken together, this data seems to suggest WBV may be used as a viable way to decrease arterial stiffness. Special populations, such as post-stroke patients, may be unwilling or unable to perform WBV exercise so an inactive form of exercise (vibration) therapy is needed. Passive vibration (PV), allows patients to lie in an inactive, supine position, with their legs placed onto the vibration plate. This exposes the lower limbs to continuous vibration without performing voluntary muscle contraction. PV has been shown to increase skin blood flow on the vibrated extremity through vasodilation in healthy individuals and type 2 diabetics. Previous work in our laboratory has demonstrated that a 10-min session of PV on the legs decreases augmentation index (AIx) , a marker of pressure wave reflection, as well as leg and systemic PW
Primary Outcome
Non-invasive measures of brachial blood pressure
Interventions
- OTHER Low-Frequency Passive Vibration
- OTHER High-Frequency Pasive Vibration
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2012-01 |
| Est. Completion | 2012-07 |
| Phase | NA |
What the finished NCT01841840 record still lists
NCT01841840 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Low-Frequency Passive Vibration is the first listed.
NCT01841840 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01841840 about?
NCT01841840 is a clinical study titled "The Acute Effects of Passive Vibration on Cardiovascular Function in Individuals With Stroke". Stroke is the third leading cause of death in the United States. Of those who are affected by stroke, a third becomes permanently disabled. Risk factors for stroke include, but are not limited to, advancing age, physical inactivity, arterial stiffness, and most commonly, high blood pressure. Stroke ...
What is the current status of trial NCT01841840?
This trial is currently completed. It is a NA study. The enrollment target is 11 participants. The study started on 2012-01. Estimated completion is 2012-07.
What interventions are being tested in trial NCT01841840?
The interventions under investigation include: Low-Frequency Passive Vibration (OTHER), High-Frequency Pasive Vibration (OTHER).
Who is sponsoring clinical trial NCT01841840?
This trial is sponsored by Florida State University, which has 219 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01841840's enrollment target sits among peer trials
11 1927th of 2000 higher than 74 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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