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NCT01838434 · ClinicalTrials.gov registry record · Phase 1

Lenalidomide With or Without Idelalisib in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

A Phase 1 study, sponsored by Alliance for Clinical Trials in Oncology.

Completed
Registry status
Phase 1
Development phase
106
Enrollment target

NCT01838434: Completed Phase 1 study, sponsored by Alliance for Clinical Trials in Oncology.

NCT01838434 is a Phase 1 study that has completed, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 106 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01838434, a Phase 1 study, has completed, sponsored by Alliance for Clinical Trials in Oncology.

COMPLETED
Registry status
Phase 1
Development phase
106 participants
Enrollment target

Study Summary

This Phase I/II trial studies the safety and effectiveness of lenalidomide with or without idelalisib. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. Idelalisib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. It is not yet known whether lenalidomide is more effective with or without idelalisib in treating mantle cell lymphoma.

Interventions

  • DRUG lenalidomide
  • DRUG idelalisib

Trial Details

FieldValue
Enrollment Target 106 participants
Start Date 2013-10-17
Est. Completion 2017-05-01
Phase Phase 1

What the finished NCT01838434 record still lists

NCT01838434 is an interventional study that assigns participants to a tested intervention. The registered 106 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% higher).

The record links to 0 conditions, and to 2 interventions - of which lenalidomide is the first listed.

NCT01838434 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01838434 about?

NCT01838434 is a clinical study titled "Lenalidomide With or Without Idelalisib in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma". This Phase I/II trial studies the safety and effectiveness of lenalidomide with or without idelalisib. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. Idelalisib may stop the growth of cancer cells by blocking some of ...

What is the current status of trial NCT01838434?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 106 participants. The study started on 2013-10-17. Estimated completion is 2017-05-01.

What interventions are being tested in trial NCT01838434?

The interventions under investigation include: lenalidomide (DRUG), idelalisib (DRUG).

Who is sponsoring clinical trial NCT01838434?

This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01838434's enrollment target sits among peer trials

106 531st of 2000 higher than 1,468 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01838434, the US trial registry maintained by the National Library of Medicine. NCT01838434 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.