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NCT01827670 · ClinicalTrials.gov registry record · Phase 3
Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity
A Phase 3 study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 3
- Development phase
- 119
- Enrollment target
NCT01827670: Completed Phase 3 study, sponsored by GlaxoSmithKline.
NCT01827670 is a Phase 3 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 119 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01827670, a Phase 3 study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 119 participants
- Enrollment target
Study Summary
Clinical studies have demonstrated long term relief from dentine hypersensitivity with twice daily brushing of a toothpaste containing stannous fluoride in comparison to marketed (negative) controls. The aim of this study is to evaluate the effectiveness of a stannous fluoride dentifrice in the treatment of dentinal hypersensitivity compared to a marketed (negative) control, over a period of 56 days (8 weeks) with twice daily brushing.
Primary Outcome
The examiner conducted the evaporative air sensitivity assessment and scored the subject's response to the sensitivity stimulus using the four-point categorical Schiff Sensitivity Scale (SSS). Score 0 = Subject does not respond to air stimulus Score 1 = Subject responds to air stimulus, but does not request discontinuation of stimulus Score 2 = Subject responds to air stimulus, and requests discontinuation or moves from stimulus Score 3 = Subject responds to air stimulus, considers stimulus to
Interventions
- DRUG Stannous fluoride
- DRUG Sodium monofluorophosphate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 119 participants |
| Start Date | 2013-02 |
| Est. Completion | 2013-05 |
| Phase | Phase 3 |
What the finished NCT01827670 record still lists
NCT01827670 is an interventional study that assigns participants to a tested intervention. The registered 119 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 2 interventions - of which Stannous fluoride is the first listed.
NCT01827670 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01827670 about?
NCT01827670 is a clinical study titled "Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity". Clinical studies have demonstrated long term relief from dentine hypersensitivity with twice daily brushing of a toothpaste containing stannous fluoride in comparison to marketed (negative) controls. The aim of this study is to evaluate the effectiveness of a stannous fluoride dentifrice in the trea...
What is the current status of trial NCT01827670?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 119 participants. The study started on 2013-02. Estimated completion is 2013-05.
What interventions are being tested in trial NCT01827670?
The interventions under investigation include: Stannous fluoride (DRUG), Sodium monofluorophosphate (DRUG).
Who is sponsoring clinical trial NCT01827670?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01827670's enrollment target sits among peer trials
119 1640th of 2000 higher than 360 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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