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NCT01825902 · ClinicalTrials.gov registry record · Early Phase 1

18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma

A Early Phase 1 study, sponsored by Mayo Clinic.

Completed
Registry status
Early Phase 1
Development phase
1
Enrollment target

NCT01825902: Completed Early Phase 1 study, sponsored by Mayo Clinic.

NCT01825902 is a Early Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 1 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01825902, a Early Phase 1 study, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Early Phase 1
Development phase
1 participants
Enrollment target

Study Summary

This pilot trial studies fluorine F 18 fluorothymidine (18F-FLT) positron emission tomography and diffusion-weighted magnetic resonance imaging in planing surgery and radiation therapy and measuring response in patients with newly diagnosed Ewing sarcoma. Comparing results of diagnostic procedures done before and after treatment may help doctors predict a patient's response and help plan the best treatment.

Primary Outcome

The primary measure of the samples will be % of viable malignant cells remaining. To examine the correlation of 18F-FLT PET, 18F-FDG PET, and ADC signals in areas of concordance and discordance with standard MR imaging as it impacts differentiation of viable and necrotic tumor extent, sensitivity/specificity and positive/negative predictive values will be estimated. Findings will be summarized using point-estimates and corresponding 95% confidence intervals as appropriate. Differences in sensiti

Interventions

  • OTHER laboratory biomarker analysis
  • RADIATION fludeoxyglucose F 18
  • PROCEDURE positron emission tomography
  • PROCEDURE diffusion-weighted magnetic resonance imaging
  • DRUG fluorine F 18 fluorothymidine

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2013-03
Est. Completion 2015-11-23
Phase Early Phase 1
Mayo Clinic

2,844 total trials

What the finished NCT01825902 record still lists

NCT01825902 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 5 interventions - of which laboratory biomarker analysis is the first listed.

NCT01825902 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01825902 about?

NCT01825902 is a clinical study titled "18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma". This pilot trial studies fluorine F 18 fluorothymidine (18F-FLT) positron emission tomography and diffusion-weighted magnetic resonance imaging in planing surgery and radiation therapy and measuring response in patients with newly diagnosed Ewing sarcoma. Comparing results of diagnostic procedures d...

What is the current status of trial NCT01825902?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 1 participants. The study started on 2013-03. Estimated completion is 2015-11-23.

What interventions are being tested in trial NCT01825902?

The interventions under investigation include: laboratory biomarker analysis (OTHER), fludeoxyglucose F 18 (RADIATION), positron emission tomography (PROCEDURE), diffusion-weighted magnetic resonance imaging (PROCEDURE), fluorine F 18 fluorothymidine (DRUG).

Who is sponsoring clinical trial NCT01825902?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01825902's enrollment target sits among peer trials

1 1985th of 2000 the lowest of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01825902, the US trial registry maintained by the National Library of Medicine. NCT01825902 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.