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NCT01822132 · ClinicalTrials.gov registry record · NA

Risky Decision Making in Methamphetamine Users: The Role of Opioid Blockade

A NA study, sponsored by Oregon Health and Science University.

Completed
Registry status
NA
Development phase
76
Enrollment target

NCT01822132: Completed NA study, sponsored by Oregon Health and Science University.

NCT01822132 is a NA study that has completed, run by Oregon Health and Science University. The registered enrollment target is 76 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01822132, a NA study, has completed, sponsored by Oregon Health and Science University.

COMPLETED
Registry status
NA
Development phase
76 participants
Enrollment target

Study Summary

The purpose of this protocol is to learn more about impulsive decision making in people who use methamphetamines. The investigators would like to know if a medication called naltrexone changes how people make decisions. The investigators would also like to know whether changes in decision making can be observed by MRI (magnetic resonance imaging). The research is conducted in Portland, OR.

Primary Outcome

In the SexPD task, subjects are asked to choose between having sex with a more appealing partner with a varying chance of having a sexually transmitted infection (STI) or a less appealing partner with no STI. A hyperbolic decay model was used to calculate h, a free parameter that indexes the rate of probabilistic discounting. Smaller h values indicate a preference for probabilistic (i.e., riskier) outcomes. To normalize the data, the natural log of h values were calculated and reported here.

Interventions

  • DRUG Placebo
  • DRUG Extended release naltrexone

Trial Details

FieldValue
Enrollment Target 76 participants
Start Date 2013-05
Est. Completion 2015-03
Phase NA

What the finished NCT01822132 record still lists

NCT01822132 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01822132 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01822132 about?

NCT01822132 is a clinical study titled "Risky Decision Making in Methamphetamine Users: The Role of Opioid Blockade". The purpose of this protocol is to learn more about impulsive decision making in people who use methamphetamines. The investigators would like to know if a medication called naltrexone changes how people make decisions. The investigators would also like to know whether changes in decision making can...

What is the current status of trial NCT01822132?

This trial is currently completed. It is a NA study. The enrollment target is 76 participants. The study started on 2013-05. Estimated completion is 2015-03.

What interventions are being tested in trial NCT01822132?

The interventions under investigation include: Placebo (DRUG), Extended release naltrexone (DRUG).

Who is sponsoring clinical trial NCT01822132?

This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01822132's enrollment target sits among peer trials

76 1062nd of 2000 higher than 932 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01822132, the US trial registry maintained by the National Library of Medicine. NCT01822132 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.