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NCT01819831 · ClinicalTrials.gov registry record · NA

A Phase II Trial of Preoperative Proton Therapy in Soft-tissue Sarcomas of the Extremities and Body Wall

A NA study, sponsored by Loma Linda University.

Completed
Registry status
NA
Development phase
7
Enrollment target

NCT01819831 is a NA study that has completed, run by Loma Linda University. The registered enrollment target is 7 participants.

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The verdict

NCT01819831, a NA study, has completed, sponsored by Loma Linda University.

COMPLETED
Registry status
NA
Development phase
7 participants
Enrollment target

Study Summary

When treated with surgery alone, many soft-tissue sarcomas have a high chance of coming back. Radiation therapy is frequently used in addition to surgery to reduce the chances of the sarcoma coming back. However, radiation can have long-term side effects on the normal tissues surrounding the tumor, leading to problems such as swelling, scarring, and joint stiffness. Recently, there have been advances in the way that radiation therapy can be given. Proton radiation therapy is one of those advances. With proton radiation, it is possible to give radiation over a smaller area surrounding the tumor, resulting in less radiation to the surrounding normal tissues. The purpose of this study is to determine whether proton radiation decreases the long-term side effects of radiation on normal tissues and if smaller proton radiation fields reduce local recurrence compared to the larger radiation fields that have been used in prior studies.

Interventions

  • RADIATION proton radiation
  • PROCEDURE surgery (wide local excision; limb preservation surgery)

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 2013-02-27
Est. Completion 2022-05-19
Phase NA

Sponsor

Loma Linda University

237 total trials

What the Registry Record Tells You About NCT01819831

The ClinicalTrials.gov registry entry for NCT01819831 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 7 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Loma Linda University, which has 237 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which proton radiation is the first listed.

NCT01819831 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01819831 about?

NCT01819831 is a clinical study titled "A Phase II Trial of Preoperative Proton Therapy in Soft-tissue Sarcomas of the Extremities and Body Wall". When treated with surgery alone, many soft-tissue sarcomas have a high chance of coming back. Radiation therapy is frequently used in addition to surgery to reduce the chances of the sarcoma coming back. However, radiation can have long-term side effects on the normal tissues surrounding the tumor, ...

What is the current status of trial NCT01819831?

This trial is currently completed. It is a NA study. The enrollment target is 7 participants. The study started on 2013-02-27. Estimated completion is 2022-05-19.

What interventions are being tested in trial NCT01819831?

The interventions under investigation include: proton radiation (RADIATION), surgery (wide local excision; limb preservation surgery) (PROCEDURE).

Who is sponsoring clinical trial NCT01819831?

This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.