Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01817296 · ClinicalTrials.gov registry record · NA

Klinefelter Fertility Preservation

A NA study, sponsored by Boston Children's Hospital.

Completed
Registry status
NA
Development phase
15
Enrollment target

NCT01817296 is a NA study that has completed, run by Boston Children's Hospital. The registered enrollment target is 15 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01817296, a NA study, has completed, sponsored by Boston Children's Hospital.

COMPLETED
Registry status
NA
Development phase
15 participants
Enrollment target

Study Summary

Klinefelter syndrome occurs in 1 in 600 males and is a common cause of infertility in men. It appears scar tissue forms in these boys' testicles, leading to progressive destruction over their lifetimes. Advanced reproductive technology can be used to surgically retrieve sperm from these individuals, but these methods have a 50% failure rate in adult Klinefelter patients. Younger men have higher success rates, suggesting that adolescence and young adulthood may be the best time to extract sperm, but these techniques have not been studied in Klinefelter patients younger than 26 years of age. Additionally, there is currently no way to predict which Klinefelter patients will have success with these methods and which of them will not. This trial will explore sperm extraction in Klinefelter syndrome in an age range (12-25 years) that has never been studied, with the ultimate hope of improving the potential for fertility in these patients. The specific goals of this study are to determine the ideal age for sperm retrieval in Klinefelter patients and to establish factors that can be used to predict which of these patients will have a higher likelihood of success with advanced reproductive technology. The hypothesis is that younger Klinefelter patients will have higher sperm retrieval rates.

Interventions

  • PROCEDURE Testicular Biopsy

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2013-03
Phase NA

Sponsor

Boston Children's Hospital

462 total trials

What the Registry Record Tells You About NCT01817296

The ClinicalTrials.gov registry entry for NCT01817296 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Boston Children's Hospital, which has 462 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Testicular Biopsy is the first listed.

NCT01817296 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01817296 about?

NCT01817296 is a clinical study titled "Klinefelter Fertility Preservation". Klinefelter syndrome occurs in 1 in 600 males and is a common cause of infertility in men. It appears scar tissue forms in these boys' testicles, leading to progressive destruction over their lifetimes. Advanced reproductive technology can be used to surgically retrieve sperm from these individuals,...

What is the current status of trial NCT01817296?

This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2013-03.

What interventions are being tested in trial NCT01817296?

The interventions under investigation include: Testicular Biopsy (PROCEDURE).

Who is sponsoring clinical trial NCT01817296?

This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.