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NCT01815840 · ClinicalTrials.gov registry record · Phase 2

A Study of Two Vismodegib Regimens in Participants With Multiple Basal Cell Carcinomas

A Phase 2 study, sponsored by Hoffmann-La Roche.

Completed
Registry status
Phase 2
Development phase
229
Enrollment target

NCT01815840 is a Phase 2 study that has completed, run by Hoffmann-La Roche. The registered enrollment target is 229 participants.

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The verdict

NCT01815840, a Phase 2 study, has completed, sponsored by Hoffmann-La Roche.

COMPLETED
Registry status
Phase 2
Development phase
229 participants
Enrollment target

Study Summary

This randomized, double-blind, regimen-controlled, phase II, multicenter study will assess the efficacy and safety of two different vismodegib regimens in participants with multiple basal cell carcinoma. Participants will receive vismodegib 150 mg orally once daily either in an intermittent schedule of 12 weeks vismodegib followed by 8 weeks placebo (Arm A) or as 24 weeks induction followed by an intermittent schedule of 8 weeks placebo followed by 8 weeks vismodegib (Arm B). Anticipated time on study treatment is 72 weeks.

Interventions

  • DRUG Placebo
  • DRUG Vismodegib

Trial Details

FieldValue
Enrollment Target 229 participants
Start Date 2013-04-30
Est. Completion 2016-08-31
Phase Phase 2

Sponsor

Hoffmann-La Roche

909 total trials

What the Registry Record Tells You About NCT01815840

The ClinicalTrials.gov registry entry for NCT01815840 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 229 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hoffmann-La Roche, which has 909 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01815840 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01815840 about?

NCT01815840 is a clinical study titled "A Study of Two Vismodegib Regimens in Participants With Multiple Basal Cell Carcinomas". This randomized, double-blind, regimen-controlled, phase II, multicenter study will assess the efficacy and safety of two different vismodegib regimens in participants with multiple basal cell carcinoma. Participants will receive vismodegib 150 mg orally once daily either in an intermittent schedule...

What is the current status of trial NCT01815840?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 229 participants. The study started on 2013-04-30. Estimated completion is 2016-08-31.

What interventions are being tested in trial NCT01815840?

The interventions under investigation include: Placebo (DRUG), Vismodegib (DRUG).

Who is sponsoring clinical trial NCT01815840?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.