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NCT01803048 · ClinicalTrials.gov registry record
Predicting Cognitive and Emotional Health From Neurocircuitry Following TBI
A clinical trial, sponsored by University of Arizona.
- Completed
- Registry status
- 190
- Enrollment target
NCT01803048 is a clinical trial that has completed, run by University of Arizona. The registered enrollment target is 190 participants.
The verdict
NCT01803048 has completed, sponsored by University of Arizona.
- COMPLETED
- Registry status
- 190 participants
- Enrollment target
Study Summary
Abnormalities in structural and functional connectivity between brain regions have been suggested as putative biomarkers of mild traumatic brain injury (TBI) and significant contributors to neuropsychological functioning and injury outcome. The purpose of this study is to use two advanced magnetic resonance imaging (MRI) techniques called diffusion-weighted imaging (DWI) and resting state functional MRI to compare structural and functional connectivity between individuals with documented mild TBI and healthy controls. To evaluate the significance of structural and functional connectivity for behavior, the brain imaging data will then be related to measures of cognition and emotion. Over a 4-year period, 150 adults with documented mild TBI and 30 healthy controls will participate in the study. The study will investigate the following questions and hypotheses: 1. Evaluate the DWI metric fractional anisotropy (FA) as a measure of white matter integrity across multiple stages of recovery following mild TBI relative to healthy controls. It is hypothesized that mild TBI will be associated with greater white matter abnormalities than healthy controls. 2. It is hypothesized that there will be a relationship between FA, cognition and emotion as a function of the injury. 3. It is hypothesized that functional connectivity will be related to FA.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 190 participants |
| Start Date | 2013-02 |
| Est. Completion | 2019-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01803048
The ClinicalTrials.gov registry entry for NCT01803048 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 190 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Arizona, which has 349 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01803048 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01803048 about?
NCT01803048 is a clinical study titled "Predicting Cognitive and Emotional Health From Neurocircuitry Following TBI". Abnormalities in structural and functional connectivity between brain regions have been suggested as putative biomarkers of mild traumatic brain injury (TBI) and significant contributors to neuropsychological functioning and injury outcome. The purpose of this study is to use two advanced magnetic r...
What is the current status of trial NCT01803048?
This trial is currently completed. The enrollment target is 190 participants. The study started on 2013-02. Estimated completion is 2019-12.
Who is sponsoring clinical trial NCT01803048?
This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.
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