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NCT01800370 · ClinicalTrials.gov registry record · Phase 1
The Effect of Mixed Exercise and Metabolic Stress in Relationship to Age in Healthy Men
A Phase 1 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
NCT01800370: Completed Phase 1 study, sponsored by Mayo Clinic.
NCT01800370 is a Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01800370, a Phase 1 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
Study Summary
Aging in men reduces the amount of luteinizing hormone (LH) and testosterone (Te) secreted in each burst. Stress-associated mechanisms introduced by acute illness and chronic disease decrease LH and Te secretion further. A major unresolved issue is whether the aging process heightens the negative effects of a stressor (whether physical or metabolic) upon LH and Te secretion. This study will assess LH and Te secretion in response to a physical stressor (maximal exercise) and a common metabolic stressor (hyperglycemia) as a function of age in healthy men ages 18-80 yr.
Primary Outcome
During the exercise visit subjects will perform an exercise test on a bike and lift weights with both arms for a total of 30 minutes.
Interventions
- OTHER Exercise
- DRUG Saline
- PROCEDURE Blood Draws
- DRUG Hyperglycemia
- OTHER Fasting procedure
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2013-02 |
| Est. Completion | 2014-04 |
| Phase | Phase 1 |
What the finished NCT01800370 record still lists
NCT01800370 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).
The record links to 0 conditions, and to 5 interventions - of which Exercise is the first listed.
NCT01800370 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01800370 about?
NCT01800370 is a clinical study titled "The Effect of Mixed Exercise and Metabolic Stress in Relationship to Age in Healthy Men". Aging in men reduces the amount of luteinizing hormone (LH) and testosterone (Te) secreted in each burst. Stress-associated mechanisms introduced by acute illness and chronic disease decrease LH and Te secretion further. A major unresolved issue is whether the aging process heightens the negative ef...
What is the current status of trial NCT01800370?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2013-02. Estimated completion is 2014-04.
What interventions are being tested in trial NCT01800370?
The interventions under investigation include: Exercise (OTHER), Saline (DRUG), Blood Draws (PROCEDURE), Hyperglycemia (DRUG), Fasting procedure (OTHER).
Who is sponsoring clinical trial NCT01800370?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01800370's enrollment target sits among peer trials
40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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