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NCT01784640 · ClinicalTrials.gov registry record · Phase 1

Pemetrexed Disodium and Hsp90 Inhibitor AUY922 in Treating Patients With Previously Treated Stage IV Non-Small Cell Lung Cancer

A Phase 1 study, sponsored by Jonsson Comprehensive Cancer Center.

Completed
Registry status
Phase 1
Development phase
13
Enrollment target

NCT01784640 is a Phase 1 study that has completed, run by Jonsson Comprehensive Cancer Center. The registered enrollment target is 13 participants.

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The verdict

NCT01784640, a Phase 1 study, has completed, sponsored by Jonsson Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
13 participants
Enrollment target

Study Summary

This phase I trial studies the side effects and the best dose of Hsp90 inhibitor AUY922 when given together with pemetrexed disodium in treating patients with previously treated stage IV non-small cell lung cancer. Hsp90 inhibitor AUY922 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as pemetrexed disodium, work in different ways to stop the growth of tumor cell, either by killing the cells or stopping them from dividing. Giving Hsp90 inhibitor AUY922 together with pemetrexed disodium may kill more tumor cells

Interventions

  • OTHER laboratory biomarker analysis
  • OTHER pharmacological study
  • DRUG pemetrexed disodium
  • DRUG Hsp90 inhibitor AUY922

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2014-01-31
Est. Completion 2018-10-11
Phase Phase 1

Sponsor

Jonsson Comprehensive Cancer Center

321 total trials

What the Registry Record Tells You About NCT01784640

The ClinicalTrials.gov registry entry for NCT01784640 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 13 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jonsson Comprehensive Cancer Center, which has 321 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which laboratory biomarker analysis is the first listed.

NCT01784640 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01784640 about?

NCT01784640 is a clinical study titled "Pemetrexed Disodium and Hsp90 Inhibitor AUY922 in Treating Patients With Previously Treated Stage IV Non-Small Cell Lung Cancer". This phase I trial studies the side effects and the best dose of Hsp90 inhibitor AUY922 when given together with pemetrexed disodium in treating patients with previously treated stage IV non-small cell lung cancer. Hsp90 inhibitor AUY922 may stop the growth of tumor cells by blocking some of the enz...

What is the current status of trial NCT01784640?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 13 participants. The study started on 2014-01-31. Estimated completion is 2018-10-11.

What interventions are being tested in trial NCT01784640?

The interventions under investigation include: laboratory biomarker analysis (OTHER), pharmacological study (OTHER), pemetrexed disodium (DRUG), Hsp90 inhibitor AUY922 (DRUG).

Who is sponsoring clinical trial NCT01784640?

This trial is sponsored by Jonsson Comprehensive Cancer Center, which has 321 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.