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NCT01781104 · ClinicalTrials.gov registry record · Phase 2
Phase 2 Study to Evaluate Safety and Efficacy of RM-131 Administered to Patients With Chronic Constipation
A Phase 2 study of Constipation, sponsored by Motus Therapeutics.
- Completed
- Registry status
- Phase 2
- Development phase
- 48
- Enrollment target
- 3
- Study locations
NCT01781104: Completed Phase 2 study of Constipation, sponsored by Motus Therapeutics.
NCT01781104 is a Phase 2 study of Constipation that has completed, run by Motus Therapeutics. The registered enrollment target is 48 participants, below the 205-participant average among 54 other Constipation trials with a reported enrollment target (77% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01781104, a Phase 2 study of Constipation, has completed, sponsored by Motus Therapeutics.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 48 participants
- Enrollment target
- 3
- Study locations
Study Summary
The purpose of this study is to evaluate safety and tolerability as well as the effects of RM-131 on colonic transit, bowel consistency, bowel habits, abdominal pain, and other abdominal symptoms in patients with chronic constipation.
Primary Outcome
Change from baseline colonic geometric center at 24 hours
Conditions Studied
Interventions
- DRUG Placebo
- DRUG RM-131
Study Locations (3)
Arizona
- Mayo Clinic Arizona - Scottsdale
Florida
- Mayo Clinic Florida - Jacksonville
Minnesota
- Mayo Clinic Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2013-03 |
| Est. Completion | 2014-10 |
| Phase | Phase 2 |
What the finished NCT01781104 record still lists
NCT01781104 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 205-participant average among 54 other Constipation trials with a reported enrollment target (77% lower).
The record links to 1 condition, with Constipation appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT01781104 reports a single indexed study location in Arizona, Florida, Minnesota.
Frequently Asked Questions
What is clinical trial NCT01781104 about?
NCT01781104 is a clinical study titled "Phase 2 Study to Evaluate Safety and Efficacy of RM-131 Administered to Patients With Chronic Constipation". The purpose of this study is to evaluate safety and tolerability as well as the effects of RM-131 on colonic transit, bowel consistency, bowel habits, abdominal pain, and other abdominal symptoms in patients with chronic constipation.
What is the current status of trial NCT01781104?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 48 participants. The study started on 2013-03. Estimated completion is 2014-10.
What conditions does trial NCT01781104 study?
This clinical trial studies the following conditions: Constipation.
What interventions are being tested in trial NCT01781104?
The interventions under investigation include: Placebo (DRUG), RM-131 (DRUG).
Who is sponsoring clinical trial NCT01781104?
This trial is sponsored by Motus Therapeutics, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01781104 being conducted?
This trial has 3 study locations across Arizona, Florida, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Constipation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01781104's enrollment target sits among peer trials
48 37th of 54 higher than 17 of 54 other Constipation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Constipation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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