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NCT01779050 · ClinicalTrials.gov registry record · Phase 2

Effect of Trastuzumab on Disease Free Survival in Early Stage HER2-Negative Breast Cancer Patients With ERBB2 Expressing Disseminated Tumor Cells

A Phase 2 study, sponsored by Washington University School of Medicine.

Terminated
Registry status
Phase 2
Development phase
7
Enrollment target

NCT01779050 is a Phase 2 study that was terminated before completion, run by Washington University School of Medicine. The registered enrollment target is 7 participants.

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The verdict

NCT01779050, a Phase 2 study, was terminated before completion, sponsored by Washington University School of Medicine.

TERMINATED
Registry status
Phase 2
Development phase
7 participants
Enrollment target

Study Summary

This phase II trial studies the efficacy of trastuzumab treatment in breast cancer patients with stage II-III human epidermal growth factor receptor 2 (HER2)-negative tumors and HER2-expressing bone marrow disseminated tumor cells (DTCs). Administering targeted trastuzumab therapy to these patients may result in the elimination of HER2 expressing disseminated tumor cells and improved disease free survival.

Interventions

  • DRUG Cyclophosphamide
  • DRUG Doxorubicin
  • DRUG Paclitaxel
  • BIOLOGICAL Trastuzumab
  • DRUG Epirubicin

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 2013-12-19
Est. Completion 2021-09-01
Phase Phase 2

What the Registry Record Tells You About NCT01779050

The ClinicalTrials.gov registry entry for NCT01779050 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 7 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Cyclophosphamide is the first listed.

NCT01779050 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01779050 about?

NCT01779050 is a clinical study titled "Effect of Trastuzumab on Disease Free Survival in Early Stage HER2-Negative Breast Cancer Patients With ERBB2 Expressing Disseminated Tumor Cells". This phase II trial studies the efficacy of trastuzumab treatment in breast cancer patients with stage II-III human epidermal growth factor receptor 2 (HER2)-negative tumors and HER2-expressing bone marrow disseminated tumor cells (DTCs). Administering targeted trastuzumab therapy to these patients ...

What is the current status of trial NCT01779050?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 7 participants. The study started on 2013-12-19. Estimated completion is 2021-09-01.

What interventions are being tested in trial NCT01779050?

The interventions under investigation include: Cyclophosphamide (DRUG), Doxorubicin (DRUG), Paclitaxel (DRUG), Trastuzumab (BIOLOGICAL), Epirubicin (DRUG).

Who is sponsoring clinical trial NCT01779050?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.