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NCT01768897 · ClinicalTrials.gov registry record · Phase 1

CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

A Phase 1 study, sponsored by Wake Forest University Health Sciences.

Completed
Registry status
Phase 1
Development phase
67
Enrollment target

NCT01768897 is a Phase 1 study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 67 participants.

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The verdict

NCT01768897, a Phase 1 study, has completed, sponsored by Wake Forest University Health Sciences.

COMPLETED
Registry status
Phase 1
Development phase
67 participants
Enrollment target

Study Summary

This phase I trial studies the side effects and best dose of CPI-613 when given together with cytarabine and mitoxantrone hydrochloride in treating patients with relapsed or refractory acute myeloid leukemia. Drugs used in chemotherapy, such as CPI-613, cytarabine and mitoxantrone hydrochloride, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. CPI-613 may help cytarabine and mitoxantrone hydrochloride work better by making cancer cells more sensitive to the drugs

Interventions

  • OTHER laboratory biomarker analysis
  • OTHER pharmacological study
  • DRUG CPI-613
  • DRUG cytarabine
  • DRUG mitoxantrone hydrochloride

Trial Details

FieldValue
Enrollment Target 67 participants
Start Date 2013-01
Est. Completion 2016-01
Phase Phase 1

Sponsor

Wake Forest University Health Sciences

1,140 total trials

What the Registry Record Tells You About NCT01768897

The ClinicalTrials.gov registry entry for NCT01768897 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 67 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Wake Forest University Health Sciences, which has 1,140 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which laboratory biomarker analysis is the first listed.

NCT01768897 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01768897 about?

NCT01768897 is a clinical study titled "CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia". This phase I trial studies the side effects and best dose of CPI-613 when given together with cytarabine and mitoxantrone hydrochloride in treating patients with relapsed or refractory acute myeloid leukemia. Drugs used in chemotherapy, such as CPI-613, cytarabine and mitoxantrone hydrochloride, wor...

What is the current status of trial NCT01768897?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 67 participants. The study started on 2013-01. Estimated completion is 2016-01.

What interventions are being tested in trial NCT01768897?

The interventions under investigation include: laboratory biomarker analysis (OTHER), pharmacological study (OTHER), CPI-613 (DRUG), cytarabine (DRUG), mitoxantrone hydrochloride (DRUG).

Who is sponsoring clinical trial NCT01768897?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.