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NCT01759303 · ClinicalTrials.gov registry record · Phase 2

Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung

A Phase 2 study, sponsored by Emerald Clinical.

Terminated
Registry status
Phase 2
Development phase
12
Enrollment target

NCT01759303: Clinical Trial Phase 2 study, sponsored by Emerald Clinical.

NCT01759303 is a Phase 2 study that was terminated before completion, run by Emerald Clinical. The registered enrollment target is 12 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01759303, a Phase 2 study, was terminated before completion, sponsored by Emerald Clinical.

TERMINATED
Registry status
Phase 2
Development phase
12 participants
Enrollment target

Study Summary

The purpose of this study is to determine the 4-month Progression-Free Survival (PFS), with demonstrated increase in tumor doubling time, of eligible subjects treated with pazopanib according to RECIST version 1.1 guidelines.

Primary Outcome

The primary objective of the study is to evaluate the 4-month PFS (with demonstrated increase in tumor doubling time) of eligible subjects treated with pazopanib according to RECIST version 1.1 guidelines. Tumor growth rate will be calculated by measuring growth at the specified intervals for the single, longest dimension of the tumor(s) (RECIST) and by calculating the area of the tumor(s), which will be the product of the longest dimension of the tumor(s) multiplied by its longest, perpendicul

Interventions

  • DRUG pazopanib

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2013-04
Est. Completion 2017-05
Phase Phase 2
Emerald Clinical

4 total trials

Why NCT01759303 stopped before completion

NCT01759303 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower).

The record links to 0 conditions, and to 1 intervention - of which pazopanib is the first listed.

NCT01759303 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01759303 about?

NCT01759303 is a clinical study titled "Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung". The purpose of this study is to determine the 4-month Progression-Free Survival (PFS), with demonstrated increase in tumor doubling time, of eligible subjects treated with pazopanib according to RECIST version 1.1 guidelines.

What is the current status of trial NCT01759303?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2013-04. Estimated completion is 2017-05.

What interventions are being tested in trial NCT01759303?

The interventions under investigation include: pazopanib (DRUG).

Who is sponsoring clinical trial NCT01759303?

This trial is sponsored by Emerald Clinical, which has 4 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01759303's enrollment target sits among peer trials

12 1948th of 2000 higher than 34 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01759303, the US trial registry maintained by the National Library of Medicine. NCT01759303 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.