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NCT01754987 · ClinicalTrials.gov registry record · Phase 1
A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective
A Phase 1 study of Metastatic Hepatocellular Carcinoma and Advanced Liver Cancer, sponsored by Thomas Jefferson University.
- Completed
- Registry status
- Phase 1
- Development phase
- 5
- Enrollment target
- 1
- Study location
NCT01754987 is a Phase 1 study of Metastatic Hepatocellular Carcinoma and Advanced Liver Cancer that has completed, run by Thomas Jefferson University. The registered enrollment target is 5 participants, below the 103-participant average among 11 other Metastatic Hepatocellular Carcinoma trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01754987, a Phase 1 study of Metastatic Hepatocellular Carcinoma and Advanced Liver Cancer, has completed, sponsored by Thomas Jefferson University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 5 participants
- Enrollment target
- 1
- Study location
Study Summary
This protocol is a phase I/II, study of ascorbic acid (AA) infusions combined with treatment with sorafenib versus treatment with sorafenib alone in subjects with metastatic hepatocellular carcinoma. The phase I aspect will assess the safety and efficacy of the concurrent treatments and the phase II aspect will utilize CT (computer-tomography) scans to assess overall tumor response rate and evaluate disease progression
Conditions Studied
Interventions
- DRUG Sorafenib
- DRUG Ascorbic Acid + Sorafenib
Study Locations (1)
Pennsylvania
- Thomas Jefferson University - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2012-09 |
| Est. Completion | 2016-01 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01754987
The ClinicalTrials.gov registry entry for NCT01754987 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 103-participant average among 11 other Metastatic Hepatocellular Carcinoma trials with a reported enrollment target (95% lower). The listed sponsor is Thomas Jefferson University, which has 292 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Metastatic Hepatocellular Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which Sorafenib is the first listed.
NCT01754987 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT01754987 about?
NCT01754987 is a clinical study titled "A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective". This protocol is a phase I/II, study of ascorbic acid (AA) infusions combined with treatment with sorafenib versus treatment with sorafenib alone in subjects with metastatic hepatocellular carcinoma. The phase I aspect will assess the safety and efficacy of the concurrent treatments and the phase II...
What is the current status of trial NCT01754987?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2012-09. Estimated completion is 2016-01.
What conditions does trial NCT01754987 study?
This clinical trial studies the following conditions: Metastatic Hepatocellular Carcinoma, Advanced Liver Cancer.
What interventions are being tested in trial NCT01754987?
The interventions under investigation include: Sorafenib (DRUG), Ascorbic Acid + Sorafenib (DRUG).
Who is sponsoring clinical trial NCT01754987?
This trial is sponsored by Thomas Jefferson University, which has 292 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01754987 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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