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NCT01748721 · ClinicalTrials.gov registry record · Phase 1

MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma

A Phase 1 study, sponsored by Morphotek.

Completed
Registry status
Phase 1
Development phase
27
Enrollment target

NCT01748721: Completed Phase 1 study, sponsored by Morphotek.

NCT01748721 is a Phase 1 study that has completed, run by Morphotek. The registered enrollment target is 27 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01748721, a Phase 1 study, has completed, sponsored by Morphotek.

COMPLETED
Registry status
Phase 1
Development phase
27 participants
Enrollment target

Study Summary

This phase I trial studies the side effects and best dose of MORAb-004 in treating young patients with recurrent or refractory solid tumors or lymphoma. Monoclonal antibodies, such as MORAb-004, can block cancer growth in different ways. Some block the ability of cancer to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them

Interventions

  • OTHER laboratory biomarker analysis
  • OTHER pharmacological study
  • BIOLOGICAL anti-endosialin/TEM1 monoclonal antibody MORAb-004

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2013-11
Est. Completion 2015-05
Phase Phase 1
Morphotek

20 total trials

What the finished NCT01748721 record still lists

NCT01748721 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower).

The record links to 0 conditions, and to 3 interventions - of which laboratory biomarker analysis is the first listed.

NCT01748721 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01748721 about?

NCT01748721 is a clinical study titled "MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma". This phase I trial studies the side effects and best dose of MORAb-004 in treating young patients with recurrent or refractory solid tumors or lymphoma. Monoclonal antibodies, such as MORAb-004, can block cancer growth in different ways. Some block the ability of cancer to grow and spread. Others fi...

What is the current status of trial NCT01748721?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2013-11. Estimated completion is 2015-05.

What interventions are being tested in trial NCT01748721?

The interventions under investigation include: laboratory biomarker analysis (OTHER), pharmacological study (OTHER), anti-endosialin/TEM1 monoclonal antibody MORAb-004 (BIOLOGICAL).

Who is sponsoring clinical trial NCT01748721?

This trial is sponsored by Morphotek, which has 20 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01748721's enrollment target sits among peer trials

27 1463rd of 2000 higher than 519 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01748721, the US trial registry maintained by the National Library of Medicine. NCT01748721 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.