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COMPLETED Phase 1

Low Dose Ketamine for Management of Acute Severe Pain in the Emergency Department

NCT01740492 · View on ClinicalTrials.gov ↗

Study Summary

This study aims to address both the management and evaluation of pain. The primary aim of this study is to determine the efficacy of low dose ketamine in adults with moderate to severe pain in the emergency department as compared with parenteral opioids alone. Another aim is to examine the safety of low dose ketamine compared to opioids alone. The investigators hypothesize that low dose ketamine will result in more effective pain control than morphine alone and will not be associated with an increase in adverse events.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG Ketamine 0.15mg/kg
  • DRUG Ketamine 0.3mg/kg

Study Locations (1)

Rhode Island

  • Rhode Island Hospital — Providence

Trial Details

FieldValue
Enrollment Target 75 participants
Start Date 2012-09
Est. Completion 2014-06
Phase Phase 1

Sponsor

Rhode Island Hospital

110 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT01740492

The ClinicalTrials.gov registry entry for NCT01740492 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 75 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rhode Island Hospital, which has 110 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Pain appearing as the primary indexed condition, and to 3 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT01740492 reports 1 study location spanning 1 distinct geographic area — top geographies include Rhode Island. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT01740492 about?

NCT01740492 is a clinical study titled "Low Dose Ketamine for Management of Acute Severe Pain in the Emergency Department". This study aims to address both the management and evaluation of pain. The primary aim of this study is to determine the efficacy of low dose ketamine in adults with moderate to severe pain in the emergency department as compared with parenteral opioids alone. Another aim is to examine the safety of...

What is the current status of trial NCT01740492?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 75 participants. The study started on 2012-09. Estimated completion is 2014-06.

What conditions does trial NCT01740492 study?

This clinical trial studies the following conditions: Pain. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT01740492?

The interventions under investigation include: Placebo (OTHER), Ketamine 0.15mg/kg (DRUG), Ketamine 0.3mg/kg (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT01740492?

This trial is sponsored by Rhode Island Hospital, which has 110 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT01740492 being conducted?

This trial has 1 study location across Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial