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NCT01740492 · ClinicalTrials.gov registry record · Phase 1
Low Dose Ketamine for Management of Acute Severe Pain in the Emergency Department
A Phase 1 study of Pain, sponsored by Rhode Island Hospital.
- Completed
- Registry status
- Phase 1
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT01740492: Completed Phase 1 study of Pain, sponsored by Rhode Island Hospital.
NCT01740492 is a Phase 1 study of Pain that has completed, run by Rhode Island Hospital. The registered enrollment target is 75 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01740492, a Phase 1 study of Pain, has completed, sponsored by Rhode Island Hospital.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to address both the management and evaluation of pain. The primary aim of this study is to determine the efficacy of low dose ketamine in adults with moderate to severe pain in the emergency department as compared with parenteral opioids alone. Another aim is to examine the safety of low dose ketamine compared to opioids alone. The investigators hypothesize that low dose ketamine will result in more effective pain control than morphine alone and will not be associated with an increase in adverse events.
Primary Outcome
At baseline, to assess our primary aim, efficacy of pain control, we will use patient reported pain scores and amount of rescue analgesia (parenteral morphine) received. Trained research assistants (RA) will ask participants to report their pains scores using a numerical pain rating scale (NPRS). The NPRS used will be a 0 to 10 rating scale: a rating of 0 corresponds to "no pain at all," whereas a rating of 10 is the "worst pain imaginable." Baseline NPRS will be measured after randomization, bu
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Ketamine 0.15mg/kg
- DRUG Ketamine 0.3mg/kg
Study Locations (1)
Rhode Island
- Rhode Island Hospital - Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2012-09 |
| Est. Completion | 2014-06 |
| Phase | Phase 1 |
What the finished NCT01740492 record still lists
NCT01740492 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 304-participant average among 374 other Pain trials with a reported enrollment target (75% lower).
The record links to 1 condition, with Pain appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT01740492 reports a single indexed study location in Rhode Island.
Frequently Asked Questions
What is clinical trial NCT01740492 about?
NCT01740492 is a clinical study titled "Low Dose Ketamine for Management of Acute Severe Pain in the Emergency Department". This study aims to address both the management and evaluation of pain. The primary aim of this study is to determine the efficacy of low dose ketamine in adults with moderate to severe pain in the emergency department as compared with parenteral opioids alone. Another aim is to examine the safety of...
What is the current status of trial NCT01740492?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 75 participants. The study started on 2012-09. Estimated completion is 2014-06.
What conditions does trial NCT01740492 study?
This clinical trial studies the following conditions: Pain.
What interventions are being tested in trial NCT01740492?
The interventions under investigation include: Placebo (OTHER), Ketamine 0.15mg/kg (DRUG), Ketamine 0.3mg/kg (DRUG).
Who is sponsoring clinical trial NCT01740492?
This trial is sponsored by Rhode Island Hospital, which has 130 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01740492 being conducted?
This trial has 1 study location across Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01740492's enrollment target sits among peer trials
75 208th of 374 higher than 166 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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