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NCT01735162 · ClinicalTrials.gov registry record
Study of the Prediction of Acute Kidney Injury in Children Using Risk Stratification and Biomarkers
A clinical trial, sponsored by Children's Hospital Medical Center, Cincinnati.
- Completed
- Registry status
- 184
- Enrollment target
NCT01735162: Completed study, sponsored by Children's Hospital Medical Center, Cincinnati.
NCT01735162 is a clinical trial that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 184 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01735162 has completed, sponsored by Children's Hospital Medical Center, Cincinnati.
- COMPLETED
- Registry status
- 184 participants
- Enrollment target
Study Summary
Acute kidney injury (AKI) is a common clinical event with severe consequences. In the pediatric intensive care unit (PICU), AKI occurs in almost 10% of all patients and evidence suggests that children are dying not just with AKI, but from AKI. Unfortunately, the treatment for AKI is limited to a great extent by delayed diagnosis. Reliance on markers of kidney injury that change only when significant damage has already occurred has rendered potential therapies ineffective. For this reason, identification of new markers of AKI that change early in the course of injury is paramount. While new AKI biomarkers have been identified, their performance in the general PICU population is variable. The investigators recently proposed the concept of 'renal angina' as a way to risk stratify patients in the ICU for AKI risk. In the AKI-CHERUB study, the investigators propose to study renal angina in PICU patients alone and in combination with urinary biomarkers for AKI prediction. The investigators hypothesize that renal angina will increase the predictive precision of urinary biomarkers for AKI.
Primary Outcome
Development of AKI by KDIGO Stage 2 criteria (Creatinine \> 200% baseline)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 184 participants |
| Start Date | 2012-10 |
| Est. Completion | 2014-10 |
What the finished NCT01735162 record still lists
NCT01735162 is an observational study that tracks outcomes without assigning an intervention. The registered 184 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT01735162 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01735162 about?
NCT01735162 is a clinical study titled "Study of the Prediction of Acute Kidney Injury in Children Using Risk Stratification and Biomarkers". Acute kidney injury (AKI) is a common clinical event with severe consequences. In the pediatric intensive care unit (PICU), AKI occurs in almost 10% of all patients and evidence suggests that children are dying not just with AKI, but from AKI. Unfortunately, the treatment for AKI is limited to a gre...
What is the current status of trial NCT01735162?
This trial is currently completed. The enrollment target is 184 participants. The study started on 2012-10. Estimated completion is 2014-10.
Who is sponsoring clinical trial NCT01735162?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
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