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NCT01731873 · ClinicalTrials.gov registry record
Patient Controlled Analgesia Pharmacogenetic Study
A clinical trial, sponsored by Children's Hospital Medical Center, Cincinnati.
- Completed
- Registry status
- 182
- Enrollment target
NCT01731873: Completed study, sponsored by Children's Hospital Medical Center, Cincinnati.
NCT01731873 is a clinical trial that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 182 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01731873 has completed, sponsored by Children's Hospital Medical Center, Cincinnati.
- COMPLETED
- Registry status
- 182 participants
- Enrollment target
Study Summary
The purpose of this research study is to identify factors and genes (the nucleic acid material that determines the makeup of the human body) that may be associated with acute and chronic post-surgical pain as well as develop pharmacometric models for response to opioids, like morphine and hydromorphone. While children undergioing different surgeries will be recruited for acute outcomes, children undergoing spine fusion will be followed for 10-12 months for evaluation of psychological and genomic factors affecting chronic post-surgical pain, with a goal of identifying genetic and epigenetic risk models for prediction of acute and chronic post-surgical pain. Although opioids are used every day, some children have bad reactions from their use, like breathing problems, sedation, etc. The investigators want to study factors that may be associated with pain sensitivity, opioid requirements after surgery, their metabolism, efficacy and their side-effects. The investigators expect that the information obtained in this research study will help to develop effective, safer, and tailored treatment options in the future.
Primary Outcome
Post-surgical pain scores at rest and on mobilization, opioid requirements/48 hours
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 182 participants |
| Start Date | 2012-01-17 |
| Est. Completion | 2019-04-30 |
What the finished NCT01731873 record still lists
NCT01731873 is an observational study that tracks outcomes without assigning an intervention. The registered 182 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT01731873 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01731873 about?
NCT01731873 is a clinical study titled "Patient Controlled Analgesia Pharmacogenetic Study". The purpose of this research study is to identify factors and genes (the nucleic acid material that determines the makeup of the human body) that may be associated with acute and chronic post-surgical pain as well as develop pharmacometric models for response to opioids, like morphine and hydromorph...
What is the current status of trial NCT01731873?
This trial is currently completed. The enrollment target is 182 participants. The study started on 2012-01-17. Estimated completion is 2019-04-30.
Who is sponsoring clinical trial NCT01731873?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
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