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NCT01731873 · ClinicalTrials.gov registry record

Patient Controlled Analgesia Pharmacogenetic Study

A clinical trial, sponsored by Children's Hospital Medical Center, Cincinnati.

Completed
Registry status
182
Enrollment target

NCT01731873 is a clinical trial that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 182 participants.

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The verdict

NCT01731873 has completed, sponsored by Children's Hospital Medical Center, Cincinnati.

COMPLETED
Registry status
182 participants
Enrollment target

Study Summary

The purpose of this research study is to identify factors and genes (the nucleic acid material that determines the makeup of the human body) that may be associated with acute and chronic post-surgical pain as well as develop pharmacometric models for response to opioids, like morphine and hydromorphone. While children undergioing different surgeries will be recruited for acute outcomes, children undergoing spine fusion will be followed for 10-12 months for evaluation of psychological and genomic factors affecting chronic post-surgical pain, with a goal of identifying genetic and epigenetic risk models for prediction of acute and chronic post-surgical pain. Although opioids are used every day, some children have bad reactions from their use, like breathing problems, sedation, etc. The investigators want to study factors that may be associated with pain sensitivity, opioid requirements after surgery, their metabolism, efficacy and their side-effects. The investigators expect that the information obtained in this research study will help to develop effective, safer, and tailored treatment options in the future.

Trial Details

FieldValue
Enrollment Target 182 participants
Start Date 2012-01-17
Est. Completion 2019-04-30

What the Registry Record Tells You About NCT01731873

The ClinicalTrials.gov registry entry for NCT01731873 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 182 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Children's Hospital Medical Center, Cincinnati, which has 571 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT01731873 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01731873 about?

NCT01731873 is a clinical study titled "Patient Controlled Analgesia Pharmacogenetic Study". The purpose of this research study is to identify factors and genes (the nucleic acid material that determines the makeup of the human body) that may be associated with acute and chronic post-surgical pain as well as develop pharmacometric models for response to opioids, like morphine and hydromorph...

What is the current status of trial NCT01731873?

This trial is currently completed. The enrollment target is 182 participants. The study started on 2012-01-17. Estimated completion is 2019-04-30.

Who is sponsoring clinical trial NCT01731873?

This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.