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NCT01719094 · ClinicalTrials.gov registry record
RITHM - Resonance Imaging Trial for Heart Biomarkers in Adolescent/Young (AYA) Cancer Survivors
A clinical trial of if Aortic Stiffness and Myocardial Wall Strain, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- 101
- Enrollment target
- 2
- Study locations
NCT01719094 is a study of if Aortic Stiffness and Myocardial Wall Strain that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 101 participants. The trial reports 2 study locations across 2 states.
The verdict
NCT01719094, a study of if Aortic Stiffness and Myocardial Wall Strain, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- 101 participants
- Enrollment target
- 2
- Study locations
Study Summary
Cardiovascular events are the leading non-cancer cause of mortality after childhood cancer, occurring at a significantly younger age than in the general population. The increased incidence of cardiovascular events adversely impacts the functional capacity, morbidity, and mortality of otherwise relatively healthy 20 to 40 year old individuals. Moreover, understanding of the mechanisms by which cancer treatment could influence the occurrence of latent cardiovascular events is unavailable. Our group and others have established independent, noninvasive magnetic resonance imaging (MRI) measures of cardiovascular risk in middle aged and elderly individuals. Cardiovascular risk include, acute coronary syndromes, cardiac death, and congestive heart failure. The goal of this application is to show that childhood cancer survivors at risk for impaired cardiovascular and cerebrovascular health have increased aortic stiffness, when compared to healthy adolescent and young adult age mate. Studies are designed to determine if MRI measures of cardiovascular function differ between adolescent/adult childhood cancer survivors (n=60), age matched controls (n=30), and adolescents/young adults with planned treatment with chemo- and radiation therapy (n=25). The investigators propose that MRI markers responsible for cardiovascular events represent new clinical indicators that could be targeted to treat asymptomatic cardiovascular diseases.
Conditions Studied
Study Locations (2)
Georgia
- Emory University School of Medicine - Atlanta
North Carolina
- Wake Forset University Health Sciences - Winston-Salem
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 101 participants |
| Start Date | 2012-08 |
| Est. Completion | 2015-02 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01719094
The ClinicalTrials.gov registry entry for NCT01719094 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 101 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Wake Forest University Health Sciences, which has 1,140 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with if Aortic Stiffness appearing as the primary indexed condition, and to 0 interventions.
NCT01719094 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Georgia, North Carolina.
Frequently Asked Questions
What is clinical trial NCT01719094 about?
NCT01719094 is a clinical study titled "RITHM - Resonance Imaging Trial for Heart Biomarkers in Adolescent/Young (AYA) Cancer Survivors". Cardiovascular events are the leading non-cancer cause of mortality after childhood cancer, occurring at a significantly younger age than in the general population. The increased incidence of cardiovascular events adversely impacts the functional capacity, morbidity, and mortality of otherwise relat...
What is the current status of trial NCT01719094?
This trial is currently completed. The enrollment target is 101 participants. The study started on 2012-08. Estimated completion is 2015-02.
What conditions does trial NCT01719094 study?
This clinical trial studies the following conditions: if Aortic Stiffness, Myocardial Wall Strain.
Who is sponsoring clinical trial NCT01719094?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01719094 being conducted?
This trial has 2 study locations across Georgia, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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