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NCT01717482 · ClinicalTrials.gov registry record · Phase 2

Metformin as a Chemoprevention Agent in Non-small Cell Lung Cancer

A Phase 2 study, sponsored by Mayo Clinic.

Terminated
Registry status
Phase 2
Development phase
6
Enrollment target

NCT01717482: Clinical Trial Phase 2 study, sponsored by Mayo Clinic.

NCT01717482 is a Phase 2 study that was terminated before completion, run by Mayo Clinic. The registered enrollment target is 6 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT01717482, a Phase 2 study, was terminated before completion, sponsored by Mayo Clinic.

TERMINATED
Registry status
Phase 2
Development phase
6 participants
Enrollment target

Study Summary

The purpose of this study is to learn whether it is better to receive the drug Metformin with standard of care for lung cancer or just standard of care.

Primary Outcome

To evaluate the feasibility of patient randomization, accrual, and tissue collection in a pilot study of metformin versus observation following resection of stage IA-IIIA lung squamous cell cancer for patients by assessing the reasons patients decline randomization, tracking accrual numbers, and tracking collected tissue and reasons why tissue was not collected.

Interventions

  • DRUG Metformin
  • OTHER Placebo Comparator

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2012-10
Est. Completion 2019-05-22
Phase Phase 2
Mayo Clinic

2,844 total trials

Why NCT01717482 stopped before completion

NCT01717482 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 2 interventions - of which Metformin is the first listed.

NCT01717482 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01717482 about?

NCT01717482 is a clinical study titled "Metformin as a Chemoprevention Agent in Non-small Cell Lung Cancer". The purpose of this study is to learn whether it is better to receive the drug Metformin with standard of care for lung cancer or just standard of care.

What is the current status of trial NCT01717482?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 6 participants. The study started on 2012-10. Estimated completion is 2019-05-22.

What interventions are being tested in trial NCT01717482?

The interventions under investigation include: Metformin (DRUG), Placebo Comparator (OTHER).

Who is sponsoring clinical trial NCT01717482?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01717482's enrollment target sits among peer trials

6 1996th of 2000 higher than 1 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01717482, the US trial registry maintained by the National Library of Medicine. NCT01717482 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.