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NCT01717339 · ClinicalTrials.gov registry record · NA
Sleep Apnea and Vascular Function
A NA study, sponsored by Mayo Clinic.
- Completed
- Registry status
- NA
- Development phase
- 45
- Enrollment target
NCT01717339: Completed NA study, sponsored by Mayo Clinic.
NCT01717339 is a NA study that has completed, run by Mayo Clinic. The registered enrollment target is 45 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01717339, a NA study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 45 participants
- Enrollment target
Study Summary
Obstructive sleep apnea (OSA) is associated with endothelial dysfunction and the development of cardiovascular disease. It is unclear how OSA results in endothelial dysfunction, but given the association between OSA and obesity, adipose-derived hormones (adipokines) are likely to be involved. Leptin, an adipokine upregulated in patients with OSA, has been shown to be associated with deleterious effects on vascular function resulting in impaired endothelial function. This proposal is directed at investigating the molecular mechanisms of endothelial dysfunction in OSA patients. We hypothesize that endothelial dysfunction associated with OSA is a result of molecular alterations within endothelial cells. As a part of these studies we will look at NO signaling pathways in adipose tissue and microvessels from normal and OSA subjects.
Interventions
- OTHER Sleep Study
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2012-11 |
| Est. Completion | 2017-11 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01717339
The ClinicalTrials.gov registry entry for NCT01717339 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Sleep Study is the first listed.
NCT01717339 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01717339 about?
NCT01717339 is a clinical study titled "Sleep Apnea and Vascular Function". Obstructive sleep apnea (OSA) is associated with endothelial dysfunction and the development of cardiovascular disease. It is unclear how OSA results in endothelial dysfunction, but given the association between OSA and obesity, adipose-derived hormones (adipokines) are likely to be involved. Leptin...
What is the current status of trial NCT01717339?
This trial is currently completed. It is a NA study. The enrollment target is 45 participants. The study started on 2012-11. Estimated completion is 2017-11.
What interventions are being tested in trial NCT01717339?
The interventions under investigation include: Sleep Study (OTHER).
Who is sponsoring clinical trial NCT01717339?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
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