Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01717001 · ClinicalTrials.gov registry record
Comparison of Knee Kinematics for Subjects Implanted With Either a ConforMIS or Traditional Knee Implant
A clinical trial of Osteoarthritis, sponsored by Restor3D.
- Completed
- Registry status
- 66
- Enrollment target
- 2
- Study locations
NCT01717001: Completed study of Osteoarthritis, sponsored by Restor3D.
NCT01717001 is a study of Osteoarthritis that has completed, run by Restor3D. The registered enrollment target is 66 participants, below the 817-participant average among 135 other Osteoarthritis trials with a reported enrollment target (92% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01717001, a study of Osteoarthritis, has completed, sponsored by Restor3D.
- COMPLETED
- Registry status
- 66 participants
- Enrollment target
- 2
- Study locations
Study Summary
A better understanding of knee joint kinematics is important to explain the premature polyethylene wear failures within total knee arthroplasties (TKAs) and to help design a prosthesis that most closely approximates the normal knee. Previously, most experimental studies of knee kinematics have involved cadaveric, in vitro analyses, or have not tested the knee in a weight-bearing mode. Others have used exoskeletal linkages and skin markers that permit error due to undesired motions between markers and the underlying bone. More recently, fluoroscopy has been used to assess in vivo kinematics for subjects having a TKA. ConforMIS has attempted to follow a clearly different path than the major orthopaedic companies. They have chosen to offer patients a personalized knee implant based off of each patient's femoral and tibial bone geometry. The hypothesis is that these subjects will experience a more normal-like kinematic pattern, eliminating paradoxical anterior sliding during weight-bearing knee flexion. Therefore, the objective for this study is to analyze the in vivo kinematics for 25 patients implanted with a personalized ConforMIS TKA and 25 patients implanted with a traditional TKA design to determine if there are any kinematic differences between these TKA designs.
Primary Outcome
Comparison of amount of flexion achieved by the knee between the two arms
Conditions Studied
Study Locations (2)
Tennessee
- University of Tennessee - Knoxville
- Tennessee Orthopedic Alliance - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2012-08 |
| Est. Completion | 2014-08 |
What the finished NCT01717001 record still lists
NCT01717001 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 817-participant average among 135 other Osteoarthritis trials with a reported enrollment target (92% lower).
The record links to 1 condition, with Osteoarthritis appearing as the primary indexed condition, and to 0 interventions.
NCT01717001 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT01717001 about?
NCT01717001 is a clinical study titled "Comparison of Knee Kinematics for Subjects Implanted With Either a ConforMIS or Traditional Knee Implant". A better understanding of knee joint kinematics is important to explain the premature polyethylene wear failures within total knee arthroplasties (TKAs) and to help design a prosthesis that most closely approximates the normal knee. Previously, most experimental studies of knee kinematics have invol...
What is the current status of trial NCT01717001?
This trial is currently completed. The enrollment target is 66 participants. The study started on 2012-08. Estimated completion is 2014-08.
What conditions does trial NCT01717001 study?
This clinical trial studies the following conditions: Osteoarthritis.
Who is sponsoring clinical trial NCT01717001?
This trial is sponsored by Restor3D, which has 20 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01717001 being conducted?
This trial has 2 study locations across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01717001's enrollment target sits among peer trials
66 107th of 135 higher than 29 of 135 other Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Knee
RECRUITING · Phase 2
-
A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System
RECRUITING
-
Reliability of Pupil Response to Acute Pain
RECRUITING
-
EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))
RECRUITING · NA
-
Ketorolac in Upper Extremity Tendinopathy and Arthropathy
RECRUITING · Phase 4
-
The PROACTIVE Study for Black Elders
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02584244 · 66 participants · Phase 1
Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers
- NCT03067051 · 66 participants · Phase 1
Clinical Study to Assess the Safety and Efficacy of the SpectraCure P18 System
- NCT03754725 · 66 participants · Phase 1
Ferritin and Iron Burden in SAH sIRB
- NCT03875378 · 66 participants · Phase 2
Transdermal Estrogen in Women With Anorexia Nervosa
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia