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NCT01716416 · ClinicalTrials.gov registry record · Phase 1

Pazopanib Plus Cetuximab for Incurable Head and Neck Squamous Cell Carcinoma (HNSCC)

A Phase 1 study, sponsored by Washington University School of Medicine.

Completed
Registry status
Phase 1
Development phase
32
Enrollment target

NCT01716416 is a Phase 1 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 32 participants.

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The verdict

NCT01716416, a Phase 1 study, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
Phase 1
Development phase
32 participants
Enrollment target

Study Summary

This phase I trial studies the side effects and best dose of pazopanib hydrochloride (pazopanib) when given together with cetuximab in treating patients with incurable recurrent or metastatic head and neck cancer. Pazopanib may stop the growth of cancer by blocking blood flow to the tumor. Pazopanib may also block some of the enzymes needed for cell growth. Cetuximab is a monoclonal antibody that blocks the ability of some tumor cells to grow and spread. Giving pazopanib with cetuximab may provide a more effective treatment for patients with advanced head and neck cancer.

Interventions

  • DRUG Cetuximab
  • DRUG Pazopanib

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2013-05-31
Est. Completion 2017-08-31
Phase Phase 1

What the Registry Record Tells You About NCT01716416

The ClinicalTrials.gov registry entry for NCT01716416 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Cetuximab is the first listed.

NCT01716416 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01716416 about?

NCT01716416 is a clinical study titled "Pazopanib Plus Cetuximab for Incurable Head and Neck Squamous Cell Carcinoma (HNSCC)". This phase I trial studies the side effects and best dose of pazopanib hydrochloride (pazopanib) when given together with cetuximab in treating patients with incurable recurrent or metastatic head and neck cancer. Pazopanib may stop the growth of cancer by blocking blood flow to the tumor. Pazopanib...

What is the current status of trial NCT01716416?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2013-05-31. Estimated completion is 2017-08-31.

What interventions are being tested in trial NCT01716416?

The interventions under investigation include: Cetuximab (DRUG), Pazopanib (DRUG).

Who is sponsoring clinical trial NCT01716416?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.