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NCT01702025 · ClinicalTrials.gov registry record · Phase 1
Rapid Acclimatization to Hypoxia at Altitude
A Phase 1 study of Physiological Function in Low Oxygen Environment, sponsored by Colorado State University.
- Completed
- Registry status
- Phase 1
- Development phase
- 41
- Enrollment target
- 1
- Study location
NCT01702025: Completed Phase 1 study of Physiological Function in Low Oxygen Environment, sponsored by Colorado State University.
NCT01702025 is a Phase 1 study of Physiological Function in Low Oxygen Environment that has completed, run by Colorado State University. The registered enrollment target is 41 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01702025, a Phase 1 study of Physiological Function in Low Oxygen Environment, has completed, sponsored by Colorado State University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 41 participants
- Enrollment target
- 1
- Study location
Study Summary
In low oxygen environments, such as altitude, some adults may become ill and suffer from acute mountain sickness. Further, all adults will find that exercising becomes much more difficult when compared with exercise at lower altitudes (e.g. sea-level). The purpose of this investigation is to study the effects of two drugs that may help people adjust to high-altitude quickly, prevent them from becoming ill and improve their exercise performance. The drugs are Methazolamide and Aminophylline.
Primary Outcome
After exercising on a stationary cycle ergometer for 30 minutes at a resistance of 100 watts, research participants will complete an exercise time trial. The time taken to cycle a distance equivalent to 7.75 miles will be recorded. On a separate day the experiment will be repeated in hypoxia. It is expected that the time taken to cycle a distance equivalent to 7.75 miles will be longer in hypoxia compared to normoxia. One of the goals of this research is to determine if the hypoxia-mediated perf
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Methazolamide
- DRUG Aminophylline
- DRUG Aminophylline+Methazolamide
Study Locations (1)
Colorado
- Colorado State University, Dept. of Health and Exercise Science - Fort Collins
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2012-06 |
| Est. Completion | 2012-12 |
| Phase | Phase 1 |
What the finished NCT01702025 record still lists
NCT01702025 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% lower).
The record links to 1 condition, with Physiological Function in Low Oxygen Environment appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.
NCT01702025 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT01702025 about?
NCT01702025 is a clinical study titled "Rapid Acclimatization to Hypoxia at Altitude". In low oxygen environments, such as altitude, some adults may become ill and suffer from acute mountain sickness. Further, all adults will find that exercising becomes much more difficult when compared with exercise at lower altitudes (e.g. sea-level). The purpose of this investigation is to study t...
What is the current status of trial NCT01702025?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 41 participants. The study started on 2012-06. Estimated completion is 2012-12.
What conditions does trial NCT01702025 study?
This clinical trial studies the following conditions: Physiological Function in Low Oxygen Environment.
What interventions are being tested in trial NCT01702025?
The interventions under investigation include: Placebo (DRUG), Methazolamide (DRUG), Aminophylline (DRUG), Aminophylline+Methazolamide (DRUG).
Who is sponsoring clinical trial NCT01702025?
This trial is sponsored by Colorado State University, which has 94 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01702025 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01702025's enrollment target sits among peer trials
41 1125th of 2000 higher than 871 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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