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NCT01699607 · ClinicalTrials.gov registry record · NA

Test-retest Reproducibility of [11C]PHNO PET Using the Constant Infusion Paradigm

A NA study of Healthy and Nicotine Dependence, sponsored by Yale University.

Completed
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT01699607 is a NA study of Healthy and Nicotine Dependence that has completed, run by Yale University. The registered enrollment target is 10 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01699607, a NA study of Healthy and Nicotine Dependence, has completed, sponsored by Yale University.

COMPLETED
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

A research study designed to examine amphetamine-induced dopamine release using the PET imaging agent \[11C\]PHNO in tobacco smokers while currently smoking and during acute withdrawal and in nonsmokers. Twenty healthy men and women tobacco smokers and twenty healthy nonsmokers will be recruited. Each subject will participate in 1 MRI and up to 2 \[11C\]PHNO PET scans. On the study day subjects will participate in two \[11C\]PHNO scans (ideally, the two PET scans will be carried out in the same day). Three hours before the second PET scan, amphetamine (0.5 mg/kg, PO) will be administered. In smokers, the scan will occur at 10-21 days of smoking abstinence.

Interventions

  • DRUG Amphetamine

Study Locations (1)

Connecticut

  • Yale University - New Haven

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2012-06
Est. Completion 2013-07
Phase NA

Sponsor

Yale University

1,492 total trials

What the Registry Record Tells You About NCT01699607

The ClinicalTrials.gov registry entry for NCT01699607 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which Amphetamine is the first listed.

NCT01699607 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT01699607 about?

NCT01699607 is a clinical study titled "Test-retest Reproducibility of [11C]PHNO PET Using the Constant Infusion Paradigm". A research study designed to examine amphetamine-induced dopamine release using the PET imaging agent \[11C\]PHNO in tobacco smokers while currently smoking and during acute withdrawal and in nonsmokers. Twenty healthy men and women tobacco smokers and twenty healthy nonsmokers will be recruited. Ea...

What is the current status of trial NCT01699607?

This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2012-06. Estimated completion is 2013-07.

What conditions does trial NCT01699607 study?

This clinical trial studies the following conditions: Healthy, Nicotine Dependence.

What interventions are being tested in trial NCT01699607?

The interventions under investigation include: Amphetamine (DRUG).

Who is sponsoring clinical trial NCT01699607?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01699607 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.