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NCT01690624 · ClinicalTrials.gov registry record · Phase 1

BI 836858 Dose Escalation in Patients With Refractory or Relapsed Acute Myeloid Leukemia and in Patients With AML in Complete Remission With High Risk to Relapse

A Phase 1 study, sponsored by Boehringer Ingelheim.

Completed
Registry status
Phase 1
Development phase
30
Enrollment target

NCT01690624: Completed Phase 1 study, sponsored by Boehringer Ingelheim.

NCT01690624 is a Phase 1 study that has completed, run by Boehringer Ingelheim. The registered enrollment target is 30 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01690624, a Phase 1 study, has completed, sponsored by Boehringer Ingelheim.

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target

Study Summary

Patients with acute myeloid leukemia who experience a relapse after at least one prior regimen may be enrolled in this trial. In addition, acute myeloid leukemia patients who are in complete remission with high risk to relapse may be eligible for this trial. The trial will examine whether monotherapy with BI 836858 is safe and tolerable at escalating dose levels.

Primary Outcome

This trial was discontinued prior to reaching the primary endpoint of determining MTD.

Interventions

  • DRUG BI 836858

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2012-09-13
Est. Completion 2018-05-21
Phase Phase 1
Boehringer Ingelheim

515 total trials

What the finished NCT01690624 record still lists

NCT01690624 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower).

The record links to 0 conditions, and to 1 intervention - of which BI 836858 is the first listed.

NCT01690624 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01690624 about?

NCT01690624 is a clinical study titled "BI 836858 Dose Escalation in Patients With Refractory or Relapsed Acute Myeloid Leukemia and in Patients With AML in Complete Remission With High Risk to Relapse". Patients with acute myeloid leukemia who experience a relapse after at least one prior regimen may be enrolled in this trial. In addition, acute myeloid leukemia patients who are in complete remission with high risk to relapse may be eligible for this trial. The trial will examine whether monotherap...

What is the current status of trial NCT01690624?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2012-09-13. Estimated completion is 2018-05-21.

What interventions are being tested in trial NCT01690624?

The interventions under investigation include: BI 836858 (DRUG).

Who is sponsoring clinical trial NCT01690624?

This trial is sponsored by Boehringer Ingelheim, which has 515 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01690624's enrollment target sits among peer trials

30 1332nd of 2000 higher than 561 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01690624, the US trial registry maintained by the National Library of Medicine. NCT01690624 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.