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NCT01687166 · ClinicalTrials.gov registry record · NA

Clinical Evaluation of the Blazer Open-Irrigated Ablation Catheter for the Treatment of Paroxysmal Atrial Fibrillation

A NA study of Paroxysmal Atrial Fibrillation (PAF), sponsored by Boston Scientific Corporation.

Completed
Registry status
NA
Development phase
398
Enrollment target
20
Study locations

NCT01687166: Completed NA study of Paroxysmal Atrial Fibrillation (PAF), sponsored by Boston Scientific Corporation.

NCT01687166 is a NA study of Paroxysmal Atrial Fibrillation (PAF) that has completed, run by Boston Scientific Corporation. The registered enrollment target is 398 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01687166, a NA study of Paroxysmal Atrial Fibrillation (PAF), has completed, sponsored by Boston Scientific Corporation.

COMPLETED
Registry status
NA
Development phase
398 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to establish the safety and effectiveness of the Blazer Open-Irrigated radiofrequency ablation catheter for the treatment of drug refractory, recurrent, symptomatic, paroxysmal atrial fibrillation.

Primary Outcome

The safety of the Blazer OI catheter will be evaluated by demonstrating that the investigational group serious adverse event rate is non-inferior to that of the control group. The safety of the Blazer OI catheter will be evaluated by demonstrating that the investigational group rate of significant pulmonary vein stenosis (≥70% reduction in diameter from baseline) and atrio-esophageal fistulas is non-inferior to that of the control group.

Interventions

  • DEVICE Blazer Open-Irrigated Ablation Catheter (Boston Scientific)
  • DEVICE FDA Approved Open-Irrigated Ablation Catheter

Study Locations (20)

Florida

  • St. Vincent's Medical Center - Jacksonville
  • Baptist Hospital - Pensacola
  • Tampa General Hospital - Tampa

New York

  • New York University - New York
  • Mt. Sinai Medical Center - New York
  • Strong Memorial Hospital of the University of Rochester - Rochester

Alabama

  • University of Alabama at Birmingham - Birmingham
  • Hunstville Hospital - Huntsville

California

  • Sequoia Hospital - Redwood City
  • University of California, San Francisco - San Francisco

Georgia

  • Emory University Hospital - Atlanta
  • Georgia Health Sciences University - Augusta

Michigan

  • University of Michigan - Ann Arbor
  • William Beaumont Hospital - Royal Oak

Connecticut

  • Yale University - New Haven

Maryland

  • Union Memorial Hospital - Baltimore

Trial Details

FieldValue
Enrollment Target 398 participants
Start Date 2012-10
Est. Completion 2016-10
Phase NA
Boston Scientific Corporation

280 total trials

What the finished NCT01687166 record still lists

NCT01687166 is an interventional study that assigns participants to a tested intervention. The registered 398 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower).

The record links to 1 condition, with Paroxysmal Atrial Fibrillation (PAF) appearing as the primary indexed condition, and to 2 interventions - of which Blazer Open-Irrigated Ablation Catheter (Boston Scientific) is the first listed.

NCT01687166 names 20 study sites across 12 states, led by Florida, New York, Alabama.

Frequently Asked Questions

What is clinical trial NCT01687166 about?

NCT01687166 is a clinical study titled "Clinical Evaluation of the Blazer Open-Irrigated Ablation Catheter for the Treatment of Paroxysmal Atrial Fibrillation". The purpose of this study is to establish the safety and effectiveness of the Blazer Open-Irrigated radiofrequency ablation catheter for the treatment of drug refractory, recurrent, symptomatic, paroxysmal atrial fibrillation.

What is the current status of trial NCT01687166?

This trial is currently completed. It is a NA study. The enrollment target is 398 participants. The study started on 2012-10. Estimated completion is 2016-10.

What conditions does trial NCT01687166 study?

This clinical trial studies the following conditions: Paroxysmal Atrial Fibrillation (PAF).

What interventions are being tested in trial NCT01687166?

The interventions under investigation include: Blazer Open-Irrigated Ablation Catheter (Boston Scientific) (DEVICE), FDA Approved Open-Irrigated Ablation Catheter (DEVICE).

Who is sponsoring clinical trial NCT01687166?

This trial is sponsored by Boston Scientific Corporation, which has 280 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01687166 being conducted?

This trial has 20 study locations across Alabama, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Paroxysmal Atrial Fibrillation (PAF)

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01687166's enrollment target sits among peer trials

398 267th of 2000 higher than 1,734 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01687166, the US trial registry maintained by the National Library of Medicine. NCT01687166 (mid enrollment · wide site footprint · completed) retrieved and formatted by PlainTrial, see methodology.