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NCT01685463 · ClinicalTrials.gov registry record · NA

Transcranial Magnetic Stimulation Used to Both Measure Cortical Excitability and Explore Methamphetamine Cue Craving

A NA study, sponsored by Medical University of South Carolina.

Completed
Registry status
NA
Development phase
18
Enrollment target

NCT01685463 is a NA study that has completed, run by Medical University of South Carolina. The registered enrollment target is 18 participants.

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The verdict

NCT01685463, a NA study, has completed, sponsored by Medical University of South Carolina.

COMPLETED
Registry status
NA
Development phase
18 participants
Enrollment target

Study Summary

Specific Primary Aims include: Aim # 1. The investigators explore the feasibility of using the TMS to investigate the cortical excitability and to inhibit meth cue craving in meth dependent population. The investigators anticipate that meth elevates cortical excitability measured by motor threshold, causes changes of cortical silent period, and RC. The investigators also anticipate that paired pulse measures (short-interval intracortical inhibition, short-interval intracortical facilitation and long-interval intracortical inhibition) will be different from healthy control, which are more directly linked to glutamatergic cortical facilitation and GABAergic inhibition, respectively. Aim # 2. Given the change of the cortical excitability in meth users, the investigators will use inhibiting TMS (1 Hz) over medial prefrontal cortex to study whether TMS can be used to reduce cue craving. The investigators hypothesize that repetitive TMS reduce meth cue craving in meth dependent population compared with sham rTMS.

Interventions

  • DEVICE Transcranial Magnetic Stimulation
  • DEVICE Sham Transcranial Magnetic Stimulation

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2008-09
Est. Completion 2014-09
Phase NA

What the Registry Record Tells You About NCT01685463

The ClinicalTrials.gov registry entry for NCT01685463 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Transcranial Magnetic Stimulation is the first listed.

NCT01685463 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01685463 about?

NCT01685463 is a clinical study titled "Transcranial Magnetic Stimulation Used to Both Measure Cortical Excitability and Explore Methamphetamine Cue Craving". Specific Primary Aims include: Aim # 1. The investigators explore the feasibility of using the TMS to investigate the cortical excitability and to inhibit meth cue craving in meth dependent population. The investigators anticipate that meth elevates cortical excitability measured by motor threshold...

What is the current status of trial NCT01685463?

This trial is currently completed. It is a NA study. The enrollment target is 18 participants. The study started on 2008-09. Estimated completion is 2014-09.

What interventions are being tested in trial NCT01685463?

The interventions under investigation include: Transcranial Magnetic Stimulation (DEVICE), Sham Transcranial Magnetic Stimulation (DEVICE).

Who is sponsoring clinical trial NCT01685463?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.