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NCT01678937 · ClinicalTrials.gov registry record
Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents
A clinical trial of Immunosuppression and Liver Transplant Rejection, sponsored by Northwestern University.
- Completed
- Registry status
- 31
- Enrollment target
- 1
- Study location
NCT01678937: Completed study of Immunosuppression and Liver Transplant Rejection, sponsored by Northwestern University.
NCT01678937 is a study of Immunosuppression and Liver Transplant Rejection that has completed, run by Northwestern University. The registered enrollment target is 31 participants, below the 645-participant average among 12 other Immunosuppression trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01678937, a study of Immunosuppression and Liver Transplant Rejection, has completed, sponsored by Northwestern University.
- COMPLETED
- Registry status
- 31 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is being done with the purpose of trying to understand if and why transplant recipients may develop tolerance to their transplanted organ. Tolerance means being able to lower or take away immunosuppression (anti-rejection medications) without causing organ rejection.
Primary Outcome
* Dendritic cell assays: myeloid vs. lymphoid (CD11c; CD123); maturation and ability to process antigens (CD83; CD205); markers that have been shown to induce regulatory T cells (ILT3; ILT4). * Regulatory/Suppressor Cells (CD4+CD25+FOXP3+CD127low; and CD8+ CD28- FOXP3+CD127low cells). * Liver function and drug levels.
Conditions Studied
Interventions
- PROCEDURE Blood Draw - Rapamycin
- PROCEDURE Blood Draw from Control Subjects
- PROCEDURE Blood Draw - CyA
- PROCEDURE Blood Draw - Tacrolimus
- PROCEDURE Blood Draw - MMF
Study Locations (1)
Illinois
- Northwestern Memorial Hospital - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2007-09 |
| Est. Completion | 2008-09 |
What the finished NCT01678937 record still lists
NCT01678937 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 645-participant average among 12 other Immunosuppression trials with a reported enrollment target (95% lower).
The record links to 2 conditions, with Immunosuppression appearing as the primary indexed condition, and to 5 interventions - of which Blood Draw - Rapamycin is the first listed.
NCT01678937 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT01678937 about?
NCT01678937 is a clinical study titled "Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents". This study is being done with the purpose of trying to understand if and why transplant recipients may develop tolerance to their transplanted organ. Tolerance means being able to lower or take away immunosuppression (anti-rejection medications) without causing organ rejection.
What is the current status of trial NCT01678937?
This trial is currently completed. The enrollment target is 31 participants. The study started on 2007-09. Estimated completion is 2008-09.
What conditions does trial NCT01678937 study?
This clinical trial studies the following conditions: Immunosuppression, Liver Transplant Rejection.
What interventions are being tested in trial NCT01678937?
The interventions under investigation include: Blood Draw - Rapamycin (PROCEDURE), Blood Draw from Control Subjects (PROCEDURE), Blood Draw - CyA (PROCEDURE), Blood Draw - Tacrolimus (PROCEDURE), Blood Draw - MMF (PROCEDURE).
Who is sponsoring clinical trial NCT01678937?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01678937 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Immunosuppression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01678937's enrollment target sits among peer trials
31 9th of 12 higher than 4 of 12 other Immunosuppression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Immunosuppression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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