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COMPLETED

Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents

NCT01678937 · View on ClinicalTrials.gov ↗

Study Summary

This study is being done with the purpose of trying to understand if and why transplant recipients may develop tolerance to their transplanted organ. Tolerance means being able to lower or take away immunosuppression (anti-rejection medications) without causing organ rejection.

Interventions

  • PROCEDURE Blood Draw - Rapamycin
  • PROCEDURE Blood Draw from Control Subjects
  • PROCEDURE Blood Draw - CyA
  • PROCEDURE Blood Draw - Tacrolimus
  • PROCEDURE Blood Draw - MMF

Study Locations (1)

Illinois

  • Northwestern Memorial Hospital — Chicago

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2007-09
Est. Completion 2008-09

Sponsor

Northwestern University

1,033 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT01678937

The ClinicalTrials.gov registry entry for NCT01678937 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 31 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Northwestern University, which has 1,033 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Immunosuppression appearing as the primary indexed condition, and to 5 interventions — of which Blood Draw - Rapamycin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT01678937 reports 1 study location spanning 1 distinct geographic area — top geographies include Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT01678937 about?

NCT01678937 is a clinical study titled "Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents". This study is being done with the purpose of trying to understand if and why transplant recipients may develop tolerance to their transplanted organ. Tolerance means being able to lower or take away immunosuppression (anti-rejection medications) without causing organ rejection.

What is the current status of trial NCT01678937?

This trial is currently completed. The enrollment target is 31 participants. The study started on 2007-09. Estimated completion is 2008-09.

What conditions does trial NCT01678937 study?

This clinical trial studies the following conditions: Immunosuppression, Liver Transplant Rejection. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT01678937?

The interventions under investigation include: Blood Draw - Rapamycin (PROCEDURE), Blood Draw from Control Subjects (PROCEDURE), Blood Draw - CyA (PROCEDURE), Blood Draw - Tacrolimus (PROCEDURE), Blood Draw - MMF (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT01678937?

This trial is sponsored by Northwestern University, which has 1,033 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT01678937 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial