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NCT01674361 · ClinicalTrials.gov registry record · Phase 2

A Study of Bitopertin (RO4917838) in Combination With Selective Serotonin Reuptake Inhibitors (SSRIs) in Participants With Obsessive-Compulsive Disorder (OCD)

A Phase 2 study, sponsored by Hoffmann-La Roche.

Completed
Registry status
Phase 2
Development phase
99
Enrollment target

NCT01674361 is a Phase 2 study that has completed, run by Hoffmann-La Roche. The registered enrollment target is 99 participants.

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The verdict

NCT01674361, a Phase 2 study, has completed, sponsored by Hoffmann-La Roche.

COMPLETED
Registry status
Phase 2
Development phase
99 participants
Enrollment target

Study Summary

This multicenter, randomized, double-blind, parallel-group, placebo-controlled study will evaluate the efficacy and safety of bitopertin in combination with SSRI in participants with obsessive-compulsive disorder. Participants will be randomized to receive either bitopertin 30 milligrams (mg) or bitopertin 10 mg or placebo orally daily in addition to their background therapy with an SSRI. Participants will be allocated to one of two strata. Participants in Stratum 1 will start study drug on Day 1. Participants in Stratum 2 will receive placebo from Day 1 (placebo lead-in) and will then start study drug at the Week 2 visit. Participants in both strata will receive the study drug in addition to their background therapy with an SSRI until Week 16.

Interventions

  • DRUG Placebo
  • DRUG SSRI
  • DRUG Bitopertin

Trial Details

FieldValue
Enrollment Target 99 participants
Start Date 2012-12-31
Est. Completion 2015-04-30
Phase Phase 2

Sponsor

Hoffmann-La Roche

909 total trials

What the Registry Record Tells You About NCT01674361

The ClinicalTrials.gov registry entry for NCT01674361 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 99 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hoffmann-La Roche, which has 909 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT01674361 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01674361 about?

NCT01674361 is a clinical study titled "A Study of Bitopertin (RO4917838) in Combination With Selective Serotonin Reuptake Inhibitors (SSRIs) in Participants With Obsessive-Compulsive Disorder (OCD)". This multicenter, randomized, double-blind, parallel-group, placebo-controlled study will evaluate the efficacy and safety of bitopertin in combination with SSRI in participants with obsessive-compulsive disorder. Participants will be randomized to receive either bitopertin 30 milligrams (mg) or bit...

What is the current status of trial NCT01674361?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 99 participants. The study started on 2012-12-31. Estimated completion is 2015-04-30.

What interventions are being tested in trial NCT01674361?

The interventions under investigation include: Placebo (DRUG), SSRI (DRUG), Bitopertin (DRUG).

Who is sponsoring clinical trial NCT01674361?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.