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NCT01668147 · ClinicalTrials.gov registry record · Phase 1
Efavirenz and Ritonavir on Human Brain P-Glycoprotein
A Phase 1 study of Drug Effects, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Phase 1
- Development phase
- 13
- Enrollment target
- 1
- Study location
NCT01668147: Completed Phase 1 study of Drug Effects, sponsored by Washington University School of Medicine.
NCT01668147 is a Phase 1 study of Drug Effects that has completed, run by Washington University School of Medicine. The registered enrollment target is 13 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01668147, a Phase 1 study of Drug Effects, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 13 participants
- Enrollment target
- 1
- Study location
Study Summary
To determine the effects of ritonavir and efavirenz on the activity of P-glycoprotein in human brain.
Conditions Studied
Interventions
- DRUG [11C] desmethyl-loperamide
- OTHER Control - no pretreatment
- DRUG Oral ritonavir
- DRUG Oral efavirenz
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2012-08 |
| Est. Completion | 2016-08 |
| Phase | Phase 1 |
What the finished NCT01668147 record still lists
NCT01668147 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (78% lower).
The record links to 1 condition, with Drug Effects appearing as the primary indexed condition, and to 4 interventions - of which [11C] desmethyl-loperamide is the first listed.
NCT01668147 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT01668147 about?
NCT01668147 is a clinical study titled "Efavirenz and Ritonavir on Human Brain P-Glycoprotein". To determine the effects of ritonavir and efavirenz on the activity of P-glycoprotein in human brain.
What is the current status of trial NCT01668147?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 13 participants. The study started on 2012-08. Estimated completion is 2016-08.
What conditions does trial NCT01668147 study?
This clinical trial studies the following conditions: Drug Effects.
What interventions are being tested in trial NCT01668147?
The interventions under investigation include: [11C] desmethyl-loperamide (DRUG), Control - no pretreatment (OTHER), Oral ritonavir (DRUG), Oral efavirenz (DRUG).
Who is sponsoring clinical trial NCT01668147?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01668147 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01668147's enrollment target sits among peer trials
13 1847th of 2000 higher than 149 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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