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NCT01653028 · ClinicalTrials.gov registry record · Phase 2

Alisertib in Treating Patients With Advanced or Metastatic Sarcoma

A Phase 2 study of Recurrent Adult Soft Tissue Sarcoma and Myxofibrosarcoma, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
72
Enrollment target
20
Study locations

NCT01653028 is a Phase 2 study of Recurrent Adult Soft Tissue Sarcoma and Myxofibrosarcoma that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 72 participants, below the 82-participant average among 11 other Recurrent Adult Soft Tissue Sarcoma trials with a reported enrollment target (12% lower). The trial reports 20 study locations across 2 states.

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The verdict

NCT01653028, a Phase 2 study of Recurrent Adult Soft Tissue Sarcoma and Myxofibrosarcoma, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
72 participants
Enrollment target
20
Study locations

Study Summary

This phase II trial studies how well alisertib works in treating patients with sarcoma that has spread to other places in the body and usually cannot be cured or controlled with treatment (advanced) or has spread to other places in the body (metastatic). Alisertib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • DRUG Alisertib

Study Locations (20)

Colorado

  • The Medical Center of Aurora - Aurora
  • Boulder Community Hospital - Boulder
  • Rocky Mountain Cancer Centers-Boulder - Boulder
  • Penrose-Saint Francis Healthcare - Colorado Springs
  • Rocky Mountain Cancer Centers-Penrose - Colorado Springs
  • Porter Adventist Hospital - Denver
  • Colorado Blood Cancer Institute - Denver
  • Presbyterian - Saint Lukes Medical Center - Health One - Denver
  • Rocky Mountain Cancer Centers-Midtown - Denver
  • SCL Health Saint Joseph Hospital - Denver
  • Rocky Mountain Cancer Centers-Rose - Denver
  • Rose Medical Center - Denver
  • Colorado Cancer Research Program NCORP - Denver
  • Mercy Medical Center - Durango
  • Comprehensive Cancer Care and Research Institute of Colorado LLC - Englewood
  • Swedish Medical Center - Englewood
  • Poudre Valley Hospital - Fort Collins
  • Mountain Blue Cancer Care Center - Golden
  • North Colorado Medical Center - Greeley

Arizona

  • Mayo Clinic in Arizona - Scottsdale

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2012-08-22
Phase Phase 2

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT01653028

The ClinicalTrials.gov registry entry for NCT01653028 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 82-participant average among 11 other Recurrent Adult Soft Tissue Sarcoma trials with a reported enrollment target (12% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 8 conditions, with Recurrent Adult Soft Tissue Sarcoma appearing as the primary indexed condition, and to 2 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT01653028 reports 20 study locations spanning 2 distinct geographic areas - top geographies include Colorado, Arizona.

Frequently Asked Questions

What is clinical trial NCT01653028 about?

NCT01653028 is a clinical study titled "Alisertib in Treating Patients With Advanced or Metastatic Sarcoma". This phase II trial studies how well alisertib works in treating patients with sarcoma that has spread to other places in the body and usually cannot be cured or controlled with treatment (advanced) or has spread to other places in the body (metastatic). Alisertib may stop the growth of tumor cells ...

What is the current status of trial NCT01653028?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 72 participants. The study started on 2012-08-22.

What conditions does trial NCT01653028 study?

This clinical trial studies the following conditions: Recurrent Adult Soft Tissue Sarcoma, Myxofibrosarcoma, Recurrent Liposarcoma, Recurrent Undifferentiated Pleomorphic Sarcoma, Recurrent Malignant Peripheral Nerve Sheath Tumor.

What interventions are being tested in trial NCT01653028?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Alisertib (DRUG).

Who is sponsoring clinical trial NCT01653028?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01653028 being conducted?

This trial has 20 study locations across Arizona, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.