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NCT01651429 · ClinicalTrials.gov registry record · NA
Predicting Cognitive Resilience Against Sleep Loss
A NA study, sponsored by Mclean Hospital.
- Completed
- Registry status
- NA
- Development phase
- 48
- Enrollment target
NCT01651429: Completed NA study, sponsored by Mclean Hospital.
NCT01651429 is a NA study that has completed, run by Mclean Hospital. The registered enrollment target is 48 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01651429, a NA study, has completed, sponsored by Mclean Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
Study Summary
Resilience is the ability to cope effectively and adapt to a wide range of stressful environmental challenges. Sleep loss has been shown to reduce activity in the brain regions responsible for resilience. The ability to resist the effects of sleep loss appears to be a stable, trait-like quality. This study will attempt to predict individuals' trait-resistance to sleep loss based on their neurobiology.
Primary Outcome
It is hypothesized that, relative to vulnerable individuals, those who are highly resistant to the adverse effects of sleep loss on cognition will show: 1) increased gray matter volume in the MPFC, 2) greater white matter integrity as indicated by the Diffusion Tensor Imaging measure of fractional anisotropy (FA) values in the MPFC, 3) greater functional activation in MPFC during cognitively demanding tasks, 4) greater functional connectivity between MPFC and alerting regions of the midbrain and
Interventions
- BEHAVIORAL Sleep deprivation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2013-04 |
| Est. Completion | 2014-06 |
| Phase | NA |
What the finished NCT01651429 record still lists
NCT01651429 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Sleep deprivation is the first listed.
NCT01651429 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01651429 about?
NCT01651429 is a clinical study titled "Predicting Cognitive Resilience Against Sleep Loss". Resilience is the ability to cope effectively and adapt to a wide range of stressful environmental challenges. Sleep loss has been shown to reduce activity in the brain regions responsible for resilience. The ability to resist the effects of sleep loss appears to be a stable, trait-like quality. Thi...
What is the current status of trial NCT01651429?
This trial is currently completed. It is a NA study. The enrollment target is 48 participants. The study started on 2013-04. Estimated completion is 2014-06.
What interventions are being tested in trial NCT01651429?
The interventions under investigation include: Sleep deprivation (BEHAVIORAL).
Who is sponsoring clinical trial NCT01651429?
This trial is sponsored by Mclean Hospital, which has 140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01651429's enrollment target sits among peer trials
48 1381st of 2000 higher than 601 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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