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NCT01648205 · ClinicalTrials.gov registry record · Phase 2
Long-term Efficacy Study of Sodium Channel Blocker in LQT3 Patients
A Phase 2 study, sponsored by University of Rochester.
- Completed
- Registry status
- Phase 2
- Development phase
- 25
- Enrollment target
NCT01648205: Completed Phase 2 study, sponsored by University of Rochester.
NCT01648205 is a Phase 2 study that has completed, run by University of Rochester. The registered enrollment target is 25 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01648205, a Phase 2 study, has completed, sponsored by University of Rochester.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 25 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether late sodium channel blockade might be effective in shortening the QTc interval in various LQT3 mutations and be considered as a safe therapeutic option for LQT3 patients.
Primary Outcome
Change in QTc at 2 months on ranolazine vs. at 1 month on placebo. This was prespecified outcome.
Interventions
- DRUG Placebo
- DRUG Ranolazine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2012-09 |
| Est. Completion | 2018-07-20 |
| Phase | Phase 2 |
What the finished NCT01648205 record still lists
NCT01648205 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01648205 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01648205 about?
NCT01648205 is a clinical study titled "Long-term Efficacy Study of Sodium Channel Blocker in LQT3 Patients". The purpose of this study is to determine whether late sodium channel blockade might be effective in shortening the QTc interval in various LQT3 mutations and be considered as a safe therapeutic option for LQT3 patients.
What is the current status of trial NCT01648205?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2012-09. Estimated completion is 2018-07-20.
What interventions are being tested in trial NCT01648205?
The interventions under investigation include: Placebo (DRUG), Ranolazine (DRUG).
Who is sponsoring clinical trial NCT01648205?
This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01648205's enrollment target sits among peer trials
25 1719th of 2000 higher than 245 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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