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NCT01636804 · ClinicalTrials.gov registry record

Incidence & Predictors of Mechanical Abnormalities of QuickSite® and QuickFlex® Left Ventricular Pacing Leads

A clinical trial, sponsored by Dhanunjaya Lakkireddy, MD, FACC.

Completed
Registry status
190
Enrollment target

NCT01636804 is a clinical trial that has completed, run by Dhanunjaya Lakkireddy, MD, FACC. The registered enrollment target is 190 participants.

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The verdict

NCT01636804 has completed, sponsored by Dhanunjaya Lakkireddy, MD, FACC.

COMPLETED
Registry status
190 participants
Enrollment target

Study Summary

On April 2, 2012 the manufacturer of the Quicksite® and Quickflex® leads, St. Jude Medical, released a voluntary medical device advisory regarding these leads' potential for problems with the silicone insulation covering one end of the lead, where it meets another section of the lead which is coated with a different insulating material (polyurethane). There has been a voluntary suspension of sales of these leads. There are approximately 179,000 of the above leads implanted worldwide with an estimated 101,000 leads currently in service (59,000 in US). There have been 39 confirmed cases of the conductor portion of the lead becoming exposed from the silicone insulation (externalization), and the rate of occurrence of this type of problem is conservatively estimated at less than one percent. However, a review done by St. Jude Medical of returned Quicksite® and Quickflex® leads and available X-ray and fluoroscopic (x-ray movie) images of patients with these leads (from 1,219 patients) revealed a higher rate of 3-4%. It is presumed that there are patients whose leads have not yet been affected by this problem, but whose leads may show signs of structural changes on x-ray or fluoroscopy. This study seeks to determine what structural changes may be occurring in these leads, what signs might predict these changes, and what impact these changes may have on the lead and its performance.

Interventions

  • DEVICE Quicksite
  • DEVICE Quickflex

Trial Details

FieldValue
Enrollment Target 190 participants
Start Date 2012-07

Sponsor

Dhanunjaya Lakkireddy, MD, FACC

7 total trials

What the Registry Record Tells You About NCT01636804

The ClinicalTrials.gov registry entry for NCT01636804 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 190 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Dhanunjaya Lakkireddy, MD, FACC, which has 7 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Quicksite is the first listed.

NCT01636804 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01636804 about?

NCT01636804 is a clinical study titled "Incidence & Predictors of Mechanical Abnormalities of QuickSite® and QuickFlex® Left Ventricular Pacing Leads". On April 2, 2012 the manufacturer of the Quicksite® and Quickflex® leads, St. Jude Medical, released a voluntary medical device advisory regarding these leads' potential for problems with the silicone insulation covering one end of the lead, where it meets another section of the lead which is coated...

What is the current status of trial NCT01636804?

This trial is currently completed. The enrollment target is 190 participants. The study started on 2012-07.

What interventions are being tested in trial NCT01636804?

The interventions under investigation include: Quicksite (DEVICE), Quickflex (DEVICE).

Who is sponsoring clinical trial NCT01636804?

This trial is sponsored by Dhanunjaya Lakkireddy, MD, FACC, which has 7 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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