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NCT01624467 · ClinicalTrials.gov registry record · Phase 2

A Study of Necitumumab Monotherapy and the QT/QTc Interval in Patient With Advanced Solid Tumors

A Phase 2 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 2
Development phase
75
Enrollment target

NCT01624467: Completed Phase 2 study, sponsored by Eli Lilly and Company.

NCT01624467 is a Phase 2 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 75 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01624467, a Phase 2 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 2
Development phase
75 participants
Enrollment target

Study Summary

The purpose of this study is to determine whether treatment with necitumumab monotherapy affects the QT/QTc interval among participants with advanced solid tumors refractory to standard treatment or for which no standard treatment is available.

Primary Outcome

The corrected QT interval was calculated using Fridericia's correction (QTcF) from electrocardiogram (ECG) data. Each participant had triplicate QT intervals measured at each timepoint and the average was calculated for each participant at each timepoint. For each timepoint, a participant's corresponding baseline (Day -1, pretreatment) QTcF interval was subtracted from the average QTcF intervals to create the change from time-matched baseline in the QTcF interval

Interventions

  • BIOLOGICAL Necitumumab

Trial Details

FieldValue
Enrollment Target 75 participants
Start Date 2012-08
Est. Completion 2015-06
Phase Phase 2
Eli Lilly and Company

1,341 total trials

What the finished NCT01624467 record still lists

NCT01624467 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% lower).

The record links to 0 conditions, and to 1 intervention - of which Necitumumab is the first listed.

NCT01624467 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01624467 about?

NCT01624467 is a clinical study titled "A Study of Necitumumab Monotherapy and the QT/QTc Interval in Patient With Advanced Solid Tumors". The purpose of this study is to determine whether treatment with necitumumab monotherapy affects the QT/QTc interval among participants with advanced solid tumors refractory to standard treatment or for which no standard treatment is available.

What is the current status of trial NCT01624467?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 75 participants. The study started on 2012-08. Estimated completion is 2015-06.

What interventions are being tested in trial NCT01624467?

The interventions under investigation include: Necitumumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT01624467?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01624467's enrollment target sits among peer trials

75 900th of 2000 higher than 1,081 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01624467, the US trial registry maintained by the National Library of Medicine. NCT01624467 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.